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Neurologist (brain, nervous system)
11 years of experience
Accepting new patients
Video profile


Education ?

Medical School Score Rankings
University of Michigan Medical School (2001)
Top 25%

Awards & Distinctions ?

American Association of Neuromuscular and Electrodiagnostic Medicine
American Board of Psychiatry and Neurology

Affiliations ?

Dr. Little is affiliated with 2 hospitals.

Hospital Affiliations



  • University of Michigan Hospitals & Health Centers
    1500 E Medical Center Dr, Ann Arbor, MI 48109
    Top 25%
  • University of Michigan Health System
  • Publications & Research

    Dr. Little has contributed to 10 publications.
    Title Quality-of-care Indicators for Children with Sickle Cell Disease.
    Date April 2012
    Journal Pediatrics

    To develop a set of quality-of-care indicators for the management of children with sickle cell disease (SCD) who are cared for in a variety of settings by addressing the broad spectrum of complications relevant to their illness.

    Title Can State Early Intervention Programs Meet the Increased Demand of Children Suspected of Having Autism Spectrum Disorders?
    Date January 2011
    Journal Journal of Developmental and Behavioral Pediatrics : Jdbp

    To determine whether Early Intervention programs have the capacity to accommodate the expected increase in referrals following the American Academy of Pediatrics' 2007 recommendation for universal screening of 18- and 24-month-old children for Autism Spectrum Disorders (ASD).

    Title Diabetic Neuropathies.
    Date June 2007
    Journal Practical Neurology
    Title Marked Pleural Effusion Causing Right Atrial Collapse Simulating Cardiac Tamponade in a Dog.
    Date May 2007
    Journal Journal of the American Animal Hospital Association

    A 16-month-old, female German shepherd dog was presented with severe bicavitary effusions. A diaphragmatic hernia was diagnosed by thoracic radiography. An echocardiogram performed prior to surgical repair of the hernia revealed signs of cardiac tamponade, with right atrial collapse, in the absence of pericardial effusion. Right atrial collapse was presumed to be secondary to severe pleural effusion. At surgery, no pericardial disease was identified. Surgical correction of the diaphragmatic hernia resulted in resolution of the pleural and peritoneal effusions. Follow-up echocardiography demonstrated resolution of the signs of cardiac tamponade.

    Title Survey of Electrodiagnostic Laboratories Regarding Hemorrhagic Complications from Needle Electromyography.
    Date October 2006
    Journal Muscle & Nerve

    Little is known about the complications of needle electromyography (EMG) performed on anticoagulated patients, and no guidelines exist regarding its performance. We conducted an anonymous survey of academic EMG laboratories in the U.S. to understand current practices and complications with regard to anticoagulated patients and those receiving antiplatelet medications. Forty-seven (78%) of 60 EMG laboratories responded to the survey. Four laboratories (9%) reported at least one hemorrhagic complication requiring medical or surgical intervention in an anticoagulated patient, whereas none reported a hemorrhagic complication in patients receiving antiplatelet medications. Ten (21%) reported willingness to evaluate cranial, paraspinal, and all limb muscles in anticoagulated patients. This survey suggests that hemorrhagic complications from needle EMG of anticoagulated patients are rare. It also suggests that needle EMG of patients receiving antiplatelet therapy is not associated with increased reports of hemorrhagic complications.

    Title Nontuberculous Mycobacterial Infection of a Metastatic Brain Neoplasm in an Immunocompromised Patient.
    Date June 2006
    Journal Archives of Neurology

    BACKGROUND: Nontuberculous mycobacterial infections occur in immunocompromised patients but so rarely involve the central nervous system (CNS) that they may not be included in a differential diagnosis of CNS lesions in such patients. OBJECTIVE: To illustrate a putative mechanism for nontuberculous mycobacterial infection of the CNS via breakdown of the blood-brain barrier by metastatic neoplasm. RESULTS: A 56-year-old man who had undergone renal transplantation in February 2003 and was taking an immunosuppressive regimen of mycophenolate mofetil and cyclosporine was seen in the emergency department after a syncopal episode. Head computed tomography revealed a single focal occipital lesion with vasogenic edema. Hospital admission and further workup led to diagnosis of metastatic carcinoma infected with nontuberculous mycobacteria in the setting of a disseminated nontuberculous mycobacterial infection. CONCLUSION: This case illustrates that breakdown of the blood-brain barrier by metastatic neoplasm may provide a route of access for a pathogen that is not normally seen in the CNS.

    Title A Three-state Study of Waterborne Disease Surveillance Techniques.
    Date November 1985
    Journal American Journal of Public Health

    For a two-year period, the states of Colorado, Vermont and Washington tested the effectiveness of ten surveillance methods for identifying waterborne disease. Nine were active surveillance methods, soliciting illness reports; one was passive, relying on voluntary disease reporting. One waterborne disease outbreak was identified through use of the nine active methods, while 14 were reported through the passive surveillance method. The presence of coliform bacteria during routine water testing was not related to illness in the community.

    Title Serotyping and Serology Studies of Campylobacteriosis Associated with Consumption of Raw Milk.
    Date January 1985
    Journal Journal of Clinical Microbiology

    A community outbreak of 15 cases of gastroenteritis was traced to consumption of unpasteurized milk produced at one commercial dairy. Using two different testing schemes, we found that a Campylobacter jejuni isolate from an ill patient and an isolate from a sick cow were the same serotype. Bacteriological studies suggested that a single epidemic strain of Campylobacter jejuni caused this outbreak.

    Title Investigation of a Waterborne Outbreak of Giardiasis Using Serologic Testing by Ifa.
    Date March 1984
    Journal American Journal of Public Health
    Title Communication of Urgent Public Health Messages to Urban Populations: Lessons from the Massachusetts Water Main Break.
    Journal Disaster Medicine and Public Health Preparedness

    To study when and how an urgent public health message about a boil-water order reached an urban population after the Massachusetts water main break.

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