advertisement
Browse Health

Credentials

Publications & Research

Dr. Endress has contributed to 1 publication.
Title Pediatric-onset Multiple Sclerosis in African-american Black and European-origin White Patients.
Date March 2009
Journal Pediatric Neurology
Excerpt

Pediatric-onset multiple sclerosis is now recognized, but the association with ethnicity has not been well studied. In a retrospective review at a major teaching facility, 46 pediatric-onset multiple sclerosis patients were identified; of these, 24 were African-American black and 19 were European-origin white. Both groups were similar in mean age at onset (black, 13.6 +/- 3.36 years; white, 13.68 +/- 3.42 years) and total duration of follow-up (black, 42.7 +/- 43.5 months; white, 38.2 +/- 35.3 months), with no significant difference in time to onset of disease-modifying therapy (black, 11.2 +/- 4.7 months; white, 12.4 +/- 5.1 months). The percentage of females was higher in the black than in the white group (83% vs 47%; P = 0.014). The annualized relapse rate was significantly higher in the black than in the white group (1.80 +/- 1.14 vs 1.13 +/- 0.50; P < 0.001). These findings are consistent with data suggesting a more aggressive disease phenotype among African-American blacks with adult-onset multiple sclerosis. Larger multicenter studies are warranted to confirm the findings.

Similar doctors nearby

Dr. Michael Brody

Orthopaedic Surgery
Terre Haute, IN

Dr. Daniel Kokmeyer

Orthopaedic Surgery
Reno, NV

Dr. Vincent Puccia

Surgery
31 years experience
Terre Haute, IN

Dr. Brett Guinn

Surgery
17 years experience
Terre Haute, IN

Dr. Chris Lueking

Surgery
16 years experience
Terre Haute, IN

Dr. Mark Lynch

Surgery
29 years experience
Terre Haute, IN
Search All Similar Doctors