Browse Health
Family Practitioner, Primary Care Doctor
12 years of experience
Video profile

Education ?

Medical School Score
Ohio University (1998)
  • Currently 2 of 4 apples

Awards & Distinctions ?

Awards  
Patients' Choice Award (2011)
Compassionate Doctor Recognition (2011)
Bridges to Excellence Recognition
Bridges to Excellence Medical Home Recognition (2014 - 2017)
Level II
NCQA Physician Practice Connections - Patient Centered Medical Home (2014 - 2017)
Top 10 Doctor - City (2014)
Roseville, CA
Family Practitioner

Affiliations ?

Dr. Mach is affiliated with 5 hospitals.

Hospital Affilations

Score

Rankings

  • Sutter Roseville Medical Center
    1 Medical Plaza Dr, Roseville, CA 95661
    • Currently 4 of 4 crosses
    Top 25%
  • Mercy San Juan Medical Center
    6501 Coyle Ave, Carmichael, CA 95608
    • Currently 4 of 4 crosses
    Top 25%
  • University of California Davis Medical Center
    2315 Stockton Blvd, Sacramento, CA 95817
    • Currently 4 of 4 crosses
    Top 25%
  • Sutter Auburn Faith Hospital
    11815 Education St, Auburn, CA 95602
    • Currently 3 of 4 crosses
    Top 50%
  • UC Davis Med Center
  • Publications & Research

    Dr. Mach has contributed to 4 publications.
    Title Osmoregulatory Isoform of Dihydroxyacetone Phosphate Reductase from Dunaliella Tertiolecta: Purification and Characterization.
    Date September 2002
    Journal Protein Expression and Purification
    Excerpt

    The osmoregulatory isoform of dihydroxyacetone phosphate (DHAP) reductase (Osm-DHAPR) is an enzyme unique to Dunaliella, photosynthetic unicellular green algae adapted to extreme environments. This is the first report of purification of an isoform of DHAP reductase from Dunaliella, specifically the osmoregulatory isoform that is involved in the synthesis of free glycerol for osmoregulation in extreme environments, such as high salinity. The Osm-DHAPR is cold labile, inactivated by ammonium sulfate, forms a strong complex with Rubisco, and is unstable in the absence of glycerol. These difficulties have been addressed, and a four-step procedure has been developed to purify the Osm-DHAPR from Dunaliella tertiolecta: precipitation of Rubisco by polyethylene glycol, followed by successive chromatography on DEAE cellulose, Sephacryl S-200, and Red Agarose. Yield of the purified enzyme was 3.6%, with a specific activity of 938 micromol.min-1.mg-1 of protein and a subunit molecular mass of approximately 38 kDa. A maximum specific activity of 2580 micromol.min-1.mg-1 of protein could be achieved by assay with 150 mM NaCl. The Osm-DHAPR had little preference for NADH or NADPH, but it is highly specific for DHAP. Other metabolites of glycolysis, the tricarboxylic acid cycle, and the C3 reductive photosynthetic carbon cycle were not reduced by the enzyme. The purified enzyme was stimulated three-fold by 150 to 250 mM NaCl/KCl and by 25 mM MgCl2. Detergents, lipids, or long-chain acyl CoA derivatives, all of which inhibited the chloroplastic glyceride form of DHAP reductase, did not affect the activity of Osm-DHAPR. The Osm-DHAPR has different properties than the other chloroplastic isoform of DHAP reductase from plants and algae for glycerol phosphate formation and triglyceride synthesis.

    Title A Catalyst for Change. The Art of Strategic Mental Health Planning in Rhode Island.
    Date February 1991
    Journal The American Psychologist
    Title Fringe Visibility in Speckle Velocimetry and the Analysis of Random Flow Components.
    Date
    Journal Applied Optics
    Title Turbulence Level Measurement by Speckle Velocimetry.
    Date
    Journal Applied Optics

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