Ophthalmology, Cornea and Refractive Surgery
28 years of experience
Video profile
Accepting new patients
Texas Tech Eye Consultants
4004 82nd St # 200
Lubbock, TX 79423
806-798-7244
Locations and availability (2)

Education ?

Medical School
Univ Of Tx Health Science Center San Antonio (1982) *
Foreign school
Residency
University of California at San Francisco (1986) *
Ophthalmology
Fellowship
The Johns Hopkins Hospital (1987) *
Ophthalmology
* This information was reported to Vitals by the doctor or doctor's office.

Awards & Distinctions ?

Associations
American Board of Ophthalmology
American Academy of Ophthalmology

Affiliations ?

Dr. McCartney is affiliated with 3 hospitals.

Hospital Affilations

Score

Rankings

  • Covenant Medical Center
    3615 19th St, Lubbock, TX 79410
    • Currently 4 of 4 crosses
    Top 25%
  • University Medical Center - Lubbock *
    602 Indiana Ave, Lubbock, TX 79415
    • Currently 2 of 4 crosses
  • Covenant Children's Hospital
    3610 21st St, Lubbock, TX 79410
    • Currently 2 of 4 crosses
  • Publications & Research

    Dr. McCartney has contributed to 35 publications.
    Title Partial Agenesis of the Corpus Callosum, Hippocampal Atrophy, and Stable Intellectual Disability Associated with Roifman Syndrome.
    Date January 2012
    Journal American Journal of Medical Genetics. Part A
    Excerpt

    In 2006, we reported the cognitive and behavioral phenotype of the seventh case of Roifman syndrome (OMIM 300258). Aged 11 years 6 months, the patient displayed significant intellectual disability with proportionate impairments in attentional-executive, memory, and visuo-spatial abilities despite appearing socially "able." This discrepancy may be explained by good social-emotional skills masking his intellectual disability, by decline in cognitive abilities over time, or by unusual neuroradiological abnormalities not previously examined in Roifman syndrome. Here, we present results from a structural MRI scan, neurocognitive evaluations repeated 2 and 5 years post-baseline and assessments of face and emotional processing. The MRI revealed partial agenesis of the corpus callosum, bilateral hypoplastic hippocampi but bilaterally intact amygdala. No evidence was found for decline in the patient's neurocognitive profile. Emotional processing data indicated an age-appropriate pattern of reactivity to emotional stimuli and preserved facial identity recognition abilities, but impairments in recognition of negative facial expressions. The results confirmed a stable pattern of intellectual disability, and indicated that Roifman syndrome may be associated with major structural neuro-anatomical abnormalities. We suggest that the relative strengths in emotion and face processing are consistent with the patient's apparently able social behavior, and with intact amygdalar function.

    Title Sirolimus Therapy for Angiomyolipoma in Tuberous Sclerosis and Sporadic Lymphangioleiomyomatosis: a Phase 2 Trial.
    Date October 2011
    Journal Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
    Excerpt

    Renal angiomyolipomas are a frequent manifestation of tuberous sclerosis and sporadic lymphangioleiomyomatosis (LAM). These disorders are associated with mutations of TSC1 or TSC2 that lead to overactivation of mTOR complex 1 (mTORC1), suggesting an opportunity for targeted therapy by using mTORC1 inhibitors. This study investigated the efficacy and safety of the mTORC1 inhibitor sirolimus for treatment of renal angiomyolipomas in patients with these disorders.

    Title Growth Factors in Aqueous Humor.
    Date July 2011
    Journal Ophthalmology
    Title Time- and Temperature-dependent Stability of Growth Factor Peptides in Human Autologous Serum Eye Drops.
    Date May 2009
    Journal Cornea
    Excerpt

    To develop a step-by-step production method for human autologous serum (AS) eye drops that was broadly compliant with US Food and Drug Administration requirements for reinjection of processed biological substances. To determine optimum storage conditions for AS eye drops by measuring the concentration of growth factor peptides (GFP) as a function of storage temperature and storage duration.

    Title Serum Growth Factor Analysis in Dry Eye Syndrome.
    Date March 2009
    Journal Clinical & Experimental Ophthalmology
    Excerpt

    To perform a comprehensive serum growth factor analysis in dry eye syndrome patients and to compare this with matched controls.

    Title Sirolimus Therapy in Tuberous Sclerosis or Sporadic Lymphangioleiomyomatosis.
    Date January 2008
    Journal The New England Journal of Medicine
    Title Donor Corneal Disk Insertion Techniques in Descemetorhexis with Endokeratoplasty.
    Date December 2007
    Journal Annals of Ophthalmology (skokie, Ill.)
    Title Descemet's Stripping Automated Endothelial Keratoplasty in Intraoperative Floppy-iris Syndrome: Suture-drag Technique.
    Date August 2007
    Journal Journal of Cataract and Refractive Surgery
    Excerpt

    Descemet's stripping automated endothelial keratoplasty avoids a full-thickness corneal procedure and provides rapid visual rehabilitation. Success depends on positioning the graft successfully while minimizing intraoperative donor endothelial trauma. Previously described techniques for graft insertion may be problematic in patients with intraoperative floppy-iris syndrome, anatomically shallow or unstable anterior chambers, or increased intraoperative posterior vitreous pressure. We describe an alternative called the suture-drag technique that may facilitate lamellar endothelial graft insertion in these special circumstances.

    Title Continuous Intraocular Pressure Recordings During Lamellar Microkeratotomy of Enucleated Human Eyes.
    Date July 2007
    Journal Journal of Cataract and Refractive Surgery
    Excerpt

    PURPOSE: To analyze the course of intraocular pressure (IOP) during lamellar microkeratotomy (LMK) in enucleated human eyes using 3 microkeratome systems. SETTING: Department of Ophthalmology, Texas Tech University Health Sciences Center, Lubbock, Texas, U.S.A. METHODS: Sixteen enucleated human globes were cannulated through the optic nerve, and IOP was recorded continuously while the eyes had standard LMK flap creation. Three microkeratomes were used: Carriazo-Barraquer (Moria Inc.), Innovatome (Innovative Optics Inc.), and Hansatome (Bausch & Lomb). RESULTS: During the vacuum affixation phase, the IOP reached a mean plateau of 97.9 mm Hg with the Hansatome, 135.8 mm Hg with the Innovatome, and 150.0 mm Hg with the Carriazo-Barraquer. During applanation and cutting, the IOP rose to mean plateau of 154.7 mm Hg, 151.8 mm Hg, and 175.8 mm Hg, respectively. Statistical analysis using Kruskal-Wallis testing suggested a difference in mean IOP elevation between the 3 microkeratomes during the vacuum affixation phase (P = .0394) but no difference during the applanation and cutting phase (P = .506). CONCLUSION: The IOP during LMK was higher than previously reported, and this may increase the risk for complications in certain patient groups.

    Title Successful Treatment of Resistant Ocular Fusariosis with Posaconazole (sch-56592).
    Date February 2007
    Journal American Journal of Ophthalmology
    Excerpt

    PURPOSE: To describe the successful treatment with systemic posaconazole of a series of Fusarium ocular infections refractory to other antifungal agents. DESIGN: Retrospective, interventional case series. METHODS: We identified three patients from three different centers who received diagnoses of Fusarium keratitis and who received systemic posaconazole after their infections failed to respond to maximal tolerated medical and surgical therapy. All patients received multiple systemic, intracameral, and topical antifungal agents, which were ineffective in controlling their infection. RESULTS: Two patients were contact lens wearers. Two patients developed endophthalmitis. The infections of all three patients failed to respond to systemic and/or topical voriconazole treatment. One patient could not tolerate systemic voriconazole, and another experienced no marked improvement. The third discontinued treatment for both reasons. All patients were treated with oral posaconazole and experienced rapid reduction of intraocular inflammation and pain, as well as resolution of the infection without additional intervention. CONCLUSIONS: Deep Fusarium keratitis is difficult to treat and carries a high risk of progression to endophthalmitis. Posaconazole, which exhibits excellent tissue penetration and demonstrates efficacy in the treatment of systemic Fusarium infection, was successful in treating three cases of pan-resistant keratitis and/or endophthalmitis.

    Title Pseudallescheria Boydii Keratitis.
    Date January 2007
    Journal Scandinavian Journal of Infectious Diseases
    Excerpt

    A case of Pseudallescheria boydii keratitis is presented. The patient was successfully treated with topical natamycin and systemic itraconazole in conjunction with penetrating keratoplasty, leading to visual acuity of 20/40.

    Title The Cognitive and Behavioural Phenotype of Roifman Syndrome.
    Date December 2006
    Journal Journal of Intellectual Disability Research : Jidr
    Excerpt

    Roifman syndrome (OMIM 300258) is a multi-system disorder with a physical phenotype that includes Beta-cell immunodeficiency, intra-uterine and postnatal growth retardation, spondyloepiphyseal dysplasia, retinal dystrophy and characteristic facial dysmorphism. So far, six cases, all boys, have been reported in the literature. Roifman postulated that the syndrome may be due to a mutation in an X-linked gene or an autosomal gene giving rise to a sex-limited trait, but the definitive pathogenetic mechanism has still not been elucidated. Very little is known about the cognitive and behavioural phenotype of Roifman syndrome and no standardized measures of cognitive abilities have been reported.

    Title Visual Field Changes After Laser in Situ Keratomileusis.
    Date June 2005
    Journal Journal of Cataract and Refractive Surgery
    Excerpt

    To determine whether laser in situ keratomileusis (LASIK) affects the central 30-degree visual field.

    Title Trypan Blue in Pediatric Cataract Surgery.
    Date December 2004
    Journal Journal of Cataract and Refractive Surgery
    Title Endophthalmitis Caused by Non-perfringens Clostridium Species.
    Date December 2004
    Journal Scandinavian Journal of Infectious Diseases
    Excerpt

    The role of other non-perfringens Clostridium species in endophthalmitis infections has not been analyzed. We describe a case of non-perfringens Clostridium endophthalmitis and review prior cases in the literature. Fulminant clinical presentations and poor visual outcomes are the rule, but a combined aggressive medical and surgical approach may conserve vision.

    Title The Effect of Daily Use of Brimonidine Tartrate on the Dark-adapted Pupil Diameter.
    Date August 2004
    Journal American Journal of Ophthalmology
    Excerpt

    PURPOSE: To investigate the effect of daily brimonidine tartrate 0.15% on the dark-adapted pupil diameter. DESIGN: Observational case series. METHOD: Ten normal volunteers administered brimonidine to their right eyes once daily. Four to six hours later, infrared pupil photographs were taken after dark adaptation. Measurements were performed at baseline; on treatment days 1, 5, 11, and 18; and on washout days 1 and 2. RESULTS: One subject had no response. The nine responding subjects showed an average maximum antimydriatic effect of -1.63 mm (range, -0.57 mm--2.30 mm); all subjects experienced tachyphylaxis. Five subjects showed rebound mydriasis (mean maximum rebound +0.87 mm larger than baseline; range 0.50 mm-1.22 mm). The untreated pupil also responded, showing antimydriasis (two subjects), rebound mydriasis (two subjects), or paradoxical direct mydriasis (one subject). CONCLUSIONS: Once-daily use of brimonidine tartrate to prevent dark-induced pupil dilation can lead to tachyphylaxis and rebound mydriasis.

    Title Cluster of Diplopia Cases After Periocular Anesthesia Without Hyaluronidase.
    Date October 1999
    Journal Journal of Cataract and Refractive Surgery
    Excerpt

    PURPOSE: To describe a cluster of cases of iatrogenic diplopia after cataract surgery that occurred in 1998, when hyaluronidase was unavailable for use in periocular anesthetic regimens. SETTING: The clinical practices of the authors. METHODS: This study comprised a retrospective chart review. RESULTS: Twenty-five cases of transient or permanent diplopia were reported. Of these, 13 eyes had retrobulbar and 10 had peribulbar injections; in 2 cases the injection technique was unknown. The inferior rectus was affected in 19 eyes; of these, 1 had a temporary palsy and 18 had permanent restriction. Temporary paresis developed in the lateral rectus in 5 cases and the superior rectus in 2. Eleven cases were submitted by 4 anterior segment surgeons, who collectively had a zero incidence of iatrogenic postoperative diplopia in the preceding 4 to 11 years of practice (approximately 6900 cases). CONCLUSION: Hyaluronidase may be more important than previously suspected in preventing anesthetic-related damage to the extraocular muscles. The inferior rectus muscle is particularly vulnerable, presumably because of the injection technique.

    Title Frozen Section--guided Surgical Debridement for Management of Rhino-orbital Mucormycosis.
    Date September 1997
    Journal American Journal of Ophthalmology
    Excerpt

    PURPOSE: To present a new method of surgical treatment for rhino-orbital mucormycosis. METHOD: We treated a patient with extensive surgical debridement of mucormycosis with intraoperative frozen section guidance. The patient did not require exenteration. RESULT: Our patient survived with normal vision and no diplopia. CONCLUSIONS: Frozen section-guided surgical debridement in rhino-orbital mucormycosis may provide an alternative to traditional radical surgical excision. In selected cases, this new method of treatment may cause less morbidity than do traditional treatments.

    Title Not-for-profit Health Plans.
    Date August 1996
    Journal The New England Journal of Medicine
    Title Dual Camera Sequencer for Microsurgical Documentation.
    Date July 1991
    Journal Ophthalmic Surgery
    Excerpt

    All currently available documentary formats have inherent compromises. The use of both video and 35-mm still photography seems to be a practical solution but introduces image quality loss (when using a beam splitter type of dual camera adapter) or increased complexity of operation and resultant surgeon distraction (when using a movable mirror type of dual camera adapter). An electronic sequencer was designed to simplify the operation of a movable mirror type of dual camera adapter, permitting the efficient production of high image quality video recordings and 35-mm slides.

    Title The Choice of Posterior Chamber Intraocular Lens Style in Patients with Diabetic Retinopathy.
    Date June 1991
    Journal Archives of Ophthalmology
    Title Haemophilus Aphrophilus Endophthalmitis Associated with a Filtering Bleb.
    Date June 1991
    Journal Archives of Ophthalmology
    Title Managing Posterior Pressure During Pseudophakic Keratoplasty.
    Date October 1989
    Journal Archives of Ophthalmology
    Excerpt

    Positive vitreous pressure during penetrating keratoplasty can be difficult to manage. Despite preventive measures, positive vitreous pressure may occur and appropriate intervention is necessary to prevent serious complications. We describe a technique that may be used intraoperatively to restore a formed anterior segment and to prevent vitreous loss when persistent positive vitreous pressure occurs, while attempting to implant a pseudophakos. A 27-gauge needle, passed across the anterior chamber from limbus to limbus, just anterior to the iris, will stabilize the pseudophakos, restore the anterior chamber depth, and allow donor-tissue suturing.

    Title The Efficacy and Safety of Combined Trabeculectomy, Cataract Extraction, and Intraocular Lens Implantation.
    Date February 1989
    Journal Ophthalmology
    Excerpt

    The safety and efficacy of combined trabeculectomy, extracapsular cataract extraction (ECCE), and posterior chamber intraocular lens (PC IOL) implantation were evaluated by retrospectively analyzing 108 consecutive operations. Postoperatively, 89% of eyes achieved 20/40 or better visual acuity when preoperative macular and optic nerve diseases were excluded. Mean follow-up was 16.8 months. Intraocular pressure (IOP) control (less than or equal to 21 mmHg) was achieved in 92% of eyes; 57% required no medications. Capsulotomy (20%) and transient hyphema (15%) occurred significantly more often (P less than 0.001) than in a comparison group. These results suggest that the combined procedure gives excellent visual rehabilitation and IOP control in the majority of patients included in this analysis.

    Title Management of Selected Intraocular Lens Complications.
    Date October 1988
    Journal Transactions of the New Orleans Academy of Ophthalmology
    Title Current Surgical Management of Aphakia.
    Date October 1988
    Journal Transactions of the New Orleans Academy of Ophthalmology
    Title Changing Indications for Intraocular Lenses: Guidelines (legal and Ethical) for Cataract Surgery.
    Date October 1988
    Journal Transactions of the New Orleans Academy of Ophthalmology
    Title Current Management of Cataracts in Patients with Glaucoma.
    Date October 1988
    Journal Transactions of the New Orleans Academy of Ophthalmology
    Title Balanced Salt Solution Infusion Alert.
    Date June 1988
    Journal Archives of Ophthalmology
    Title Current Concepts in Intraocular Lens Implantation.
    Date November 1987
    Journal Developments in Ophthalmology
    Excerpt

    PC IOLs appear to be safe and effective and there are few contraindications. Based on the available data we feel confident about implanting PC IOLs in healthy eyes of patients aged 40 or older. For younger patients, we do not recommended an IOL unless glasses or contact lens use is not feasible. Caution is urged however in the use of semiflexible, closed-loop AC IOLs as well as 'soft' PC IOLs. Other questions regarding material of choice, bag versus sulcus fixation, and UV absorbers remain controversial.

    Title Intraocular Lens Style and Refraction in Eyes Treated with Silicone Oil.
    Date November 1987
    Journal Archives of Ophthalmology
    Excerpt

    The comparatively high refractive index of silicone oil significantly alters the refractive power of the human eye when it is placed into the vitreous cavity during retinal reattachment surgery. If cataract extraction and intraocular lens (IOL) implantation are subsequently performed, significant refractive errors result with most IOL styles if standard formulas are used to determine lens power. Thick-lens optical analysis of four IOL styles showed that the meniscus style yields the smallest difference between predicted (Binkhorst, Sanders-Retzlaff-Kraff formulas) and actual postoperative refraction. This IOL style also minimizes the change in refractive error that accompanies subsequent alterations in the contents of the vitreous cavity, including removal of silicone oil and replacement with balanced salt solution.

    Title Refractive Keratoplasty for Disabling Astigmatism After Penetrating Keratoplasty.
    Date August 1987
    Journal Archives of Ophthalmology
    Excerpt

    Postoperative astigmatism is one of the major limitations of penetrating keratoplasty. In an attempt to reduce postkeratoplasty astigmatism, we combined corneal-relaxing incisions with orthogonal compression sutures, guided by the intraoperative use of a ring keratometer. Eleven consecutive patients from a mixed referral population with functionally disabling astigmatism were studied. The average preoperative keratometric cylinder of 11.68 diopters was reduced by 7.95 (+/- 3.03 SD) diopters. Each patient's net keratometric cylinder was reduced. We believe that this technique is safer and more predictable than previously published techniques.

    Title Use of Posterior Chamber Lenses in Pseudophakic Bullous Keratopathy.
    Date June 1987
    Journal Archives of Ophthalmology
    Excerpt

    The occurrence of pseudophakic bullous keratopathy following anterior chamber intraocular lens implantation is well documented. At the time of penetrating keratoplasty and anterior chamber intraocular lens removal, we attempt to reimplant a posterior chamber lens whenever possible because of the complications associated with anterior chamber lenses. We developed a technique to exchange an anterior chamber lens with a posterior chamber lens during penetrating keratoplasty. The intraocular lens loops are inserted in the ciliary sulcus and the optic is sutured to the iris.

    Title Return of Vision Following Orbital Decompression After 36 Hours of Postoperative Blindness.
    Date November 1985
    Journal American Journal of Ophthalmology
    Excerpt

    A 43-year-old woman undergoing repair of an orbital floor fracture had no light perception postoperatively. Computed tomography showed a normal optic nerve and there was no optic canal fracture, intraorbital hematoma, or intraconal expansion. After a two-wall orbital decompression, visual acuity recovered to 20/70 although only an inferior nasal island of vision remained. Ductions were full and there was no blepharoptosis but a 2+ afferent pupillary defect persisted.

    Title Neuropsychological Attention Skills and Related Behaviours in Adults with Tuberous Sclerosis Complex.
    Date
    Journal Behavior Genetics
    Excerpt

    Tuberous sclerosis complex (TSC) is a genetic disorder associated with mTOR over-activation and disruption of MAPK, PI3K and AMPK signalling. Children with TSC have significant deficits on neuropsychological attention tasks, particularly dual tasking. Here we investigated attentional skills and related behaviours in daily life in normally intelligent adults with TSC and matched controls using the Test of Everyday Attention for Children (TEA-Ch) and the Attention-Deficit Scales for Adults (ADSA). No group differences were demonstrated on selective or sustained attention tasks carried out alone. However, adults with TSC performed significantly worse when these tasks were combined in a cross-modal dual task condition. On the ADSA the TSC group had significantly worse scores on several subscales (attention/concentration, behaviour/disorganization, academic and emotional behaviours) compared to controls and these correlated with dual task performance, indicating a clear impact of dual task deficits on attention-related behaviours in daily life. The presence or absence of epilepsy did not influence dual task performance or attention-deficits in daily life. Taken together with similar findings in children, results suggest that dual task difficulties are a core feature of the neuropsychological phenotype of TSC.


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