Endocrinologist (diabetes, hormones), Obstetricians & Gynecologists, Radiologist
38 years of experience

Accepting new patients
Oak Lawn
5303 Harry Hines Blvd
Dallas, TX 75390
214-648-2784
Locations and availability (4)

Education ?

Medical School Score
State University of New York Downstate (1972)
  • Currently 2 of 4 apples

Awards & Distinctions ?

Awards  
Castle Connolly's Top Doctors™ (2012 - 2013)
Associations
American Society for Reproductive Medicine
American Board of Obstetrics and Gynecology

Affiliations ?

Dr. Ackerman is affiliated with 10 hospitals.

Hospital Affilations

Score

Rankings

  • UT Southwestern University Hospital - St. Paul
    5909 Harry Hines Blvd, Dallas, TX 75235
    • Currently 4 of 4 crosses
    Top 25%
  • UT Southwestern University Hospital - Zale Lipshy
    5151 Harry Hines Blvd, Dallas, TX 75235
    • Currently 4 of 4 crosses
    Top 25%
  • Children's Medical Center of Dallas
    Obstetrician & Gynecologist
    1935 Motor St, Dallas, TX 75235
    • Currently 3 of 4 crosses
    Top 50%
  • Parkland Health & Hospital System *
    5201 Harry Hines Blvd, Dallas, TX 75235
    • Currently 1 of 4 crosses
  • UT Southwestern St. Paul Hospital
  • University Hospital - St Paul
  • Parkland Hospital
  • Dallas County Hospital District
  • Lake City VA Medical Center
  • UT Southwestern Zale Lipshy Hospital
  • * This information was reported to Vitals by the doctor or doctor's office.

    Publications & Research

    Dr. Ackerman has contributed to 8 publications.
    Title Estrogens.
    Date January 2006
    Journal Reviews in Endocrine & Metabolic Disorders
    Title Comparison of Bicarbonate and Hepes-buffered Media on Pregnancy Rates After Intrauterine Insemination with Cryopreserved Donor Sperm.
    Date October 1991
    Journal Fertility and Sterility
    Excerpt

    OBJECTIVE: We compared the pregnancy rates (PRs) after intrauterine insemination (IUI) with frozen donor sperm prepared in Ham's F-10 medium (Irvine Scientific, Santa Ana, CA) with bicarbonate buffer and synthetic human tubal fluid with HEPES buffer (Irvine Scientific). DESIGN: Women (n = 101) were randomized upon entry into the program, receiving sperm prepared in either Ham's F-10 or human tubal fluid medium their first treatment cycle. If pregnancy did not occur, the alternate medium was used to prepared sperm for the following cycle. SETTING: All patients were treated in our private care center. PATIENTS: Patients entering this study were normally ovulating women undergoing IUI with frozen donor sperm. MAIN OUTCOME MEASURE: Pregnancy was used as our main outcome measure of success. RESULTS: After 324 cycles of treatment, the PR per cycle of IUI was 17.5% with sperm prepared in human tubal fluid which was significantly different (P = 0.05) from the PR (9.8%) after insemination with sperm prepared in Ham's F-10. There was no statistical difference in the number of motile cells inseminated in each of these groups. CONCLUSIONS: Transitory exposure of the sperm in Ham's F-10 medium to the environment during preparation for insemination may result in an alkalinization of the medium that has a lasting influence on sperm fertility.

    Title Treatment of Refractory Infertility by Transcervical Intrauterine Insemination of Washed Spermatozoa.
    Date January 1988
    Journal Fertility and Sterility
    Excerpt

    One hundred thirteen couples with either male factor, cervical factor, endometriosis, or idiopathic infertility of at least 3 years' duration were treated by intrauterine insemination (IUI) of washed motile sperm. Of the 68 women who became pregnant or completed at least three cycles of insemination, the overall pregnancy rate was 38.2%, with a mean of 1.7 treatment cycles per pregnancy. The average pregnancy rate per treatment cycle was 11.4%. Women who did not become pregnant underwent an average of 4.7 treatment cycles. Importantly, only two pregnancies occurred independent of treatment in 113 couples. In the male factor group, the pregnancy rate was 42.9% (n = 21). In women with a cervical factor, 34.5% became pregnant (n = 29); in idiopathic infertile couples or women suffering from endometriosis, there was a pregnancy rate of 38.9% (n = 18). The presence of sperm antibodies in either the male or female partner significantly lowered the pregnancy rate (6.7%) when compared with couples without sperm antibodies (50.0%). The authors conclude from these observations that IUI with washed sperm is a successful mode of therapy, especially in the case of males with asthenozoospermia.

    Title Vaginal Agglutination and Hematometra Associated with Epidermolysis Bullosa.
    Date March 1987
    Journal Obstetrics and Gynecology
    Excerpt

    A case of genital involvement with epidermolysis bullosa is described. Scarring led to vaginal obstruction and hematometra. The classification and treatment of this rare disorder are discussed.

    Title Potentiation of Epinephrine-induced Lipolysis by Catechol Estrogens and Their Methoxy Derivatives.
    Date February 1982
    Journal Endocrinology
    Title Estrogen Formation in Stromal Cells of Adipose Tissue of Women: Induction by Glucocorticosteroids.
    Date January 1982
    Journal Proceedings of the National Academy of Sciences of the United States of America
    Excerpt

    Stromal cells prepared from adipose tissue of women were maintained in monolayer culture to study the regulation of aromatase activity by hormones. Aromatase activity was stimulated 20- to 100-fold by dexamethasone at a concentration of 250 nM. Half-maximal stimulation of aromatase activity was attained at a dexamethasone concentration of 2.7 nM. The stimulatory effect of dexamethasone was apparent after a preincubation time of 4 hr, and stimulation was maximal after 24 hr of preincubation. The stimulatory effect of dexamethasone was observed only when fetal calf serum also was present in the culture medium. Of the various steroids tested, dexamethasone was the most potent in stimulating aromatase activity. Cortisol was less effective than dexamethasone, whereas corticosterone, at a concentration of 250 nM, caused only a small stimulation of aromatase activity. Progesterone and deoxycorticosterone (250 nM) did not affect aromatase activity. Cytosolic fractions prepared from stromal cells that had been maintained in monolayer culture were found to contain a homogenous population of sites that specifically bound [3H]dexamethasone with relatively high affinity (Kd = 2.9 nM) and low capacity (38 fmol per mg of protein). The stimulatory effect of dexamethasone on aromatase activity was prevented by simultaneous incubation with cortisol 21-mesylate (0.1-10 microM), a compound known to block the binding of glucocorticosteroids to cytoplasmic receptors. The stimulatory effect of dexamethasone also was prevented by incubation of the cells with cycloheximide or actinomycin D. These findings are suggestive that glucocorticosteroids act to increase aromatase activity in stromal cells by inducing the synthesis of new enzyme protein.

    Title Aromatization of Androstenedione by Human Adipose Tissue Stromal Cells in Monolayer Culture.
    Date September 1981
    Journal The Journal of Clinical Endocrinology and Metabolism
    Excerpt

    Stromal cells and adipocytes were separated after collagenase treatment of adipose tissue obtained from women undergoing elective surgery, and these cells were used to study aromatization of [3H]androstenedione in vitro. Aromatization activity was estimated either 1) by determining the incorporation of tritium from [1-3H]androstenedione into [3H]water or else 2) by determining the formation of [3H]estrone (E1) and [3H]estradiol (E2) from [1,2,6,7-3H]androstenedione. It was established that only 13% of the aromatase activity of adipose tissue resided in the adipocyte fraction, whereas 87% of the aromatase activity was in the stromal/vascular fraction. Subsequent studies of aromatization were conducted utilizing stromal/vascular cells grown to confluence in monolayer culture. In such cells, the formation of [3H]E2 was slower initially but increased with time, and after 48 h of incubation, the amount of [3H]E2 produced exceeded that of [3H]E1. The rate of [3H]E1 formation, as a function of [3H]androstenedione concentration, followed Michaelis-Menten kinetics. The Vmax ranged from 0.8-3.0 pmol and ranged from 0.16-0.67 pmol mg-1 cell protein 6 h-1 in cells from omental adipose tissue. The apparent Km for [3H]androstenedione in stromal cells derived from both omental and sc tissue was the same, i.e. about 25 nM. We conclude that the ability of human adipose tissue to form estrogen is not a function primarily of the adipocytes but rather resides principally in the cells of the stroma.

    Title Sexual Assault: a Report on Human Immunodeficiency Virus Postexposure Prophylaxis.
    Date
    Journal Obstetrics and Gynecology International
    Excerpt

    The objective of this report is to describe an urban county hospital human immunodeficiency virus (HIV) infection prevention protocol offering prophylactic combination antiretroviral medications to female victims of sexual assault. A retrospective chart review was conducted from June, 2007 through June, 2008 of 151 women who were prescribed antiretroviral prophylaxis by protocol. All women receiving HIV prophylaxis initially screened HIV seronegative. Of the 58 women who reported taking any HIV prophylaxis, 36 (62%) were HIV screened at 12 and/or 24 weeks and none had HIV seroconverted. Although the initiation of an HIV post exposure prophylaxis protocol for sexual assault in a county hospital population is feasible, patient follow-up for counseling and HIV serostatus evaluation is an identified barrier.


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