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Credentials

Education ?

Medical School Score Rankings
Harvard University
  •  
Top 25%

Awards & Distinctions ?

Awards  
Castle Connolly's Top Doctors™ (2013)
Reader's Choice Award Register-Guild *
Appointments
Oregon Health & Science University%u2019s School of Medicine in Portland (2001 - Present)
Clinical Assistant Professor of Plastic Surgery
Associations
American Society of Plastic Surgeons
American Society for Aesthetic Plastic Surgery

Affiliations ?

Dr. Movassaghi is affiliated with 8 hospitals.

Hospital Affiliations

Score

Rankings

  • Sacred Heart Medical Center
    1255 Hilyard St, Eugene, OR 97401
    •  
    Top 25%
  • Peace Harbor Hospital
    400 9th St, Florence, OR 97439
    •  
    Top 50%
  • McKenzie - Willamette Medical Center
    1460 G St, Springfield, OR 97477
    •  
  • Oregon Health Science University
  • St John's Medical Center
  • Sacred Heart Medical Center - University Dist 8/10/2008 Active Current General Surgery
  • St. Joseph's Hospital
  • Sacred Heart Medical Center - RiverBend 9/13/2007 Active Current Plastic Recon Surg
  • * This information was reported to Vitals by the doctor or doctor's office.

    Publications & Research

    Dr. Movassaghi has contributed to 20 publications.
    Title Superior Antigen Cross-presentation and Xcr1 Expression Define Human Cd11c+cd141+ Cells As Homologues of Mouse Cd8+ Dendritic Cells.
    Date June 2010
    Journal The Journal of Experimental Medicine
    Excerpt

    In recent years, human dendritic cells (DCs) could be subdivided into CD304+ plasmacytoid DCs (pDCs) and conventional DCs (cDCs), the latter encompassing the CD1c+, CD16+, and CD141+ DC subsets. To date, the low frequency of these DCs in human blood has essentially prevented functional studies defining their specific contribution to antigen presentation. We have established a protocol for an effective isolation of pDC and cDC subsets to high purity. Using this approach, we show that CD141+ DCs are the only cells in human blood that express the chemokine receptor XCR1 and respond to the specific ligand XCL1 by Ca2+ mobilization and potent chemotaxis. More importantly, we demonstrate that CD141+ DCs excel in cross-presentation of soluble or cell-associated antigen to CD8+ T cells when directly compared with CD1c+ DCs, CD16+ DCs, and pDCs from the same donors. Both in their functional XCR1 expression and their effective processing and presentation of exogenous antigen in the context of major histocompatibility complex class I, human CD141+ DCs correspond to mouse CD8+ DCs, a subset known for superior antigen cross-presentation in vivo. These data define CD141+ DCs as professional antigen cross-presenting DCs in the human.

    Title Eliminating the Vertical Scar in Breast Reduction-boston Modification of the Robertson Technique.
    Date June 2009
    Journal Aesthetic Surgery Journal / the American Society for Aesthetic Plastic Surgery
    Excerpt

    Surgeons often advise patients with large ptotic breasts to undergo a Wise pattern reduction (WPR) mammaplasty using an inferior pedicle technique with consideration of a free-nipple graft.

    Title Reconstruction of the Upper Aerodigestive Tract with the Submental Artery Flap.
    Date March 2009
    Journal Plastic and Reconstructive Surgery
    Excerpt

    : The submental artery flap has rekindled interest in using cervical flaps for reconstruction of head and neck defects. In this article, the authors present their experience with this flap for defects of the upper aerodigestive tract.

    Title Massive Platelet Transfusion is a Rapidly Effective Emergency Treatment in Patients with Refractory Autoimmune Thrombocytopenia.
    Date December 2008
    Journal Thrombosis and Haemostasis
    Excerpt

    Patients with refractory autoimmune thrombocytopenia (ITP) may develop life-threatening bleeding that cannot be immediately controlled by drug administration. To date, there have been no studies conducted to evaluate the efficacy of platelet transfusion alone in such cases. Ten patients with refractory ITP and bleeding or a high bleeding risk were consecutively transfused (one unit/30 min) with apheresis platelet concentrates (APC) without the administration of new drugs. The used APCs (average 3-7 units) contained 2.7 x 10(11) (medium) platelets and were leukodepleted (< or = 1 x 10(6) leukocytes/unit). Platelet serology was performed using standard techniques. Platelet transfusion resulted in an increase in the platelet count to 84 - 157 x 10(3)/microl, and the cessation of bleeding in all patients without any serious adverse effects. Although platelet counts gradually decreased within a few days post-transfusion, bleeding was stopped in all cases. These findings indicate that consecutive platelet transfusion using APCs is a rapidly effective emergency treatment in patients with refractory ITP.

    Title The Use of Vetiver for Remediation of Heavy Metal Soil Contamination.
    Date September 2007
    Journal Analytical and Bioanalytical Chemistry
    Excerpt

    The use of Vetiveria zizanioides (vetiver) was studied to evaluate its efficiency for the remediation of soils contaminated by heavy metals. Vetiver plants were tested for Cr, Cu, Pb and Zn. Phytoextraction and bioremediation experiments were carried out by irrigating the vetiver plants and the dry plants with solutions containing suitable amounts of Cr, Cu, Pd and Zn. The concentrations of the heavy metals were determined in both experiments in shoot and root parts of vetiver plants using inductively coupled plasma atomic emission spectroscopy after a mineralization step. Phytoextraction experiments showed a poor efficiency of vetiver for Cr and Cu uptake (both less than 0.1% in shoots and roots after 30 days), but a quite high capability of Pb and Zn uptake (0.4% in shoots and 1% in roots for Pb and 1% both in shoots and in roots for Zn, after 30 days). For these reasons the vetiver plant can be considered a quite good "hyperaccumulator" only for Pb and Zn. As for bioremediation experiments, the vetiver plant showed heavy metal uptake values significantly lower than those obtained with other biological substrates.

    Title Evaluation of the Com.tec Cell Separator in Predicting the Yield of Harvested Cd34+ Cells.
    Date September 2007
    Journal Transfusion
    Excerpt

    BACKGROUND: This multicenter study was performed with the intention to evaluate the exactness of the predicted CD34+ cell yield calculated by two leukapheresis programs of the cell separator COM.TEC upon the number of donor's circulating CD34+ cells and the blood volume processed. STUDY DESIGN AND METHODS: Patients and healthy donors (n = 166) received mobilization by chemotherapy and/or granulocyte colony-stimulating factor and underwent CD34+ cell harvest by the leukapheresis programs MNC or RV-PBSC (n = 203). RESULTS: CD34+ cells were collected by 112 harvests on MNC and by 91 collections on RV-PBSC. The median collection efficiency of CD34+ cells was significantly better for the program MNC than for RV-PBSC (p < 0.001): 67% (31-109) vs. 42% (19-100). The collected CD34+ cell yield was in median more exactly by MNC than by RV-PBSC (p < 0.001): 85% (31-176) vs. 59% (22-110) of the predicted value. Concentrates obtained by RV-PBSC showed in median significantly higher percentages of mononuclear cells (p < 0.001) and CD34+ cells (p < 0.001), 86% (43-99) vs. 56% (25-95) and 1.2% (0.2-14.3) vs. 0.4% (0.1-6.0), and had lower contaminations by erythrocytes (p < 0.001) and platelets (p < 0.001), 13 mL (4-48) vs. 25 mL (5-60) and 1.9 x 1011 vs. 3.1 x 1011, than those harvested by MNC. CONCLUSION: The significantly better collection efficiency of CD34+ cells and the more exact prediction of the harvested CD34+ cell yield make the leukapheresis program MNC a safe and efficient procedure. However, concentrates collected by RV-PBSC are of a better cellular quality with a significantly higher percentage of mononuclear and CD34+ cells and a lower contamination by erythrocytes and platelets.

    Title A Preliminary Investigation of Total Organic Carbon Variation in Influent and Effluent of Isfahan (iran) Water Treatment Plant, Urban Network and Fellman Wells.
    Date January 2007
    Journal Annali Di Chimica
    Excerpt

    In this work a series of total organic carbon (TOC) analyses were carried out to analyse the influent and the effluent of a water treatment plant providing Isfahan city in Iran. Other analyses were focused on the determination of TOC in the urban network and Fellman wells (in Isfahan and Dehaghan cities), in order to compare the water quality soon after the treatment with that of circulating water in the city network. Since it supplies water treatment plant, TOC content of Zayandehrood River was also compared with the treated water. The obtained results revealed that there were significant differences between TOC content of effluent of water treatment plant and that of the urban network (made with eight different points). In this project all the samples were withdrawn during 2005. It is worth noting that the analyses were carried out with a high precision combustion-infrared method with a confidence limit lower than 0.05. The mean of TOC in Isfahan and Dehaghan Fellman wells were 0.7 and 2.6 mg.l(-1), respectively. The mean of TOC in influent of water treatment plant during June, July and September were 0.703, 1.148, 1.513 mg.l(-1) respectively which after treatment process reduced to about 0.7 mg.l(-1). In conclusion it can be said that during the summer with higher consumption of water and increase in vaporizing surface waters, we have accumulation of organic compounds and therefore we have increase in TOC content of various waters.

    Title Local Irradiation Prior to Stem Cell Harvest Has No Influence on Cd34+ Yield: a Quantitative Analysis.
    Date October 2006
    Journal Annals of Hematology
    Excerpt

    In patients with multiple myeloma, irradiation of bone marrow prior to mobilization of autologous peripheral blood progenitor cells (PBPCs) may lead to a reduced yield of CD34+ cells. Quantitative effects have not been sufficiently assessed. We retrospectively performed a multivariate analysis in 114 patients (67 men, 47 women) with multiple myeloma, of whom 53 (47%) patients had been irradiated prior to mobilization chemotherapy. High-dose cyclophosphamide followed by granulocyte colony-stimulating factor was used for mobilization in 84% of patients. In addition to previous chemotherapy, we quantitatively evaluated the dose and fractionation of prior irradiation, the volume of the irradiated bone marrow, and the time interval between radiation therapy and mobilization of PBPCs. The median volume of irradiated bone marrow was 9% (range 1-30%) of the estimated total hematopoietic bone marrow. The irradiated bone marrow volume and the number of CD34+ cells per kilogram of body weight in the first leukapheresis product showed no correlation. However, the time between irradiation and mobilization seemed to influence the yield of CD34+ cells. A comparison of irradiated patients with nonirradiated patients revealed no differences with respect to the CD34+ cell counts. We did not find a significant influence of the extent or the total dose of irradiation on the yield of CD34+ cells in the first leukapheresis product in patients with multiple myeloma. However, there may be an inverse correlation between the time elapsed since the last irradiation and the number of mobilized CD34+ cells.

    Title Cranioplasty with Subcutaneously Preserved Autologous Bone Grafts.
    Date February 2006
    Journal Plastic and Reconstructive Surgery
    Excerpt

    BACKGROUND: The efficacy of reconstructing a cranial defect with the craniectomy bone graft (bone flap) banked in a subcutaneous pocket of the abdominal wall after emergency decompressive craniotomy was evaluated. METHODS: A retrospective study was performed on 53 of 65 consecutive patients who underwent emergency decompressive craniectomy and bone graft placement in the abdominal wall and survived to graft replacement. Clinical outcome after graft replacement was determined by the adequacy of the recovered craniectomy graft to achieve satisfactory reconstruction, the incidence of infection and the need for revisional surgery. RESULTS: Forty-nine of the 53 patients (92 percent) in whom delayed autogenous graft replacement was attempted achieved a satisfactory one-stage reconstruction. In 42 of these 49 patients, autogenous graft replacement alone was performed. In eight patients it was necessary to supplement the graft with alloplastic material to achieve desired contour. One patient who underwent reconstruction with the autogenous bone graft alone, underwent late revision cranioplasty to improve contour. There were three infections. One graft was found infected in the abdominal pocket at retrieval. Two were lost to operative infection after graft replacement. Histology of two stored grafts performed after abdominal pocket retrieval demonstrated a mixture of necrotic and newly formed woven bone. A bone scan performed 1 year after graft replacement showed radionuclide activity of the graft almost identical to that of intact neighboring bone. CONCLUSIONS: Subcutaneous storage preserves viability of portions of autogenous bone grafts. Cranioplasty performed with a subcutaneously preserved craniectomy graft has a low revision rate.

    Title Optic Nerve Decompression Via Mid-facial Translocation Approach.
    Date June 2005
    Journal Annals of Plastic Surgery
    Excerpt

    Optic neuropathy is a disease complex with a broad range of etiologies that have a common end point if left untreated: blindness. Treatment varies from expectant management, medical therapy, to surgical treatment. We present a new technique for optic nerve decompression using a midfacial translocation approach. We present a case where this technique was used twice to decompress the optic nerve from an encroaching fibrous dysplasia in the same eye. Patient's vision had deteriorated to near blindness each time and it improved to its preoperative level after each surgery. This technique is especially useful in cases where the local anatomy and relevant landmarks have been distorted by the pathologic process and the surgeon requires a good exposure with minimal morbidity.

    Title Treatment of Bilateral Symptomatic Enophthalmos Associated with Weight Loss.
    Date February 2004
    Journal The Journal of Craniofacial Surgery
    Title Filgrastim-induced Stem Cell Mobilization in Chronic Myeloid Leukaemia Patients During Imatinib Therapy: Safety, Feasibility and Evidence for an Efficient in Vivo Purging.
    Date February 2004
    Journal British Journal of Haematology
    Excerpt

    Therapy with imatinib mesylate is limited by cellular resistance in chronic myeloid leukaemia (CML). Further, the limited availability of matching stem cell donors or an unfavourable risk profile for allogeneic stem cell transplantation (SCT) reduces the number of therapeutic options in a number of patients. To assess the possibility of stem cell mobilization (SCM) during imatinib therapy we performed granulocyte colony-stimulating factor (filgrastim)-induced SCM and subsequent aphaeresis in 15 chronic phase and three accelerated phase CML patients. Aphaeresis was successful in 13 patients (72%) (> or =2.0 x 10(6) CD34+ cells/kg body weight) and five (28%) harvests could be obtained, which were negative for BCR/ABL mRNA as assessed by nested-reverse transcription polymerase chain reaction (RT-PCR). All harvests, except one, were negative after first round RT-PCR, implicating a low level of CML cell contamination. There was no significant change in peripheral BCR/ABL transcript load after SCM as assessed by quantitative real-time RT-PCR. Fifteen patients remained stable in complete cytogenetic remission (CCR) during a median observation period of 9.3 months. One patient achieved a molecular remission shortly after SCM. Another patient who exhibited rising BCR/ABL mRNA levels before SCM achieved CCR after autologous SCT with the generated harvest. One patient with a Philadelphia chromosome-negative, BCR/ABL-positive CML showed a cytogenetic relapse 6 months after SCM. We conclude that filgrastim-induced CD34+ cell aphaeresis under simultaneous imatinib medication is safe and feasible in CML patients. Additionally, we found evidence that this procedure could generate stem cell harvests that exhibit non-detectable levels of BCR/ABL mRNA.

    Title Bacterial Contamination of Ex Vivo Processed Pbpc Products Under Clean Room Conditions.
    Date December 2003
    Journal Transfusion
    Excerpt

    Patients undergoing high-dose radio- and/or chemotherapy and autologous or allogeneic PBPC transplantation are at high risk for infections owing to profound immunosuppression. In this study, the rate of microbial contamination of ex vivo processed PBPC products was analyzed, comparing preparation under clean room conditions to standard laboratory conditions.

    Title First Successful Replantation of Face and Scalp with Single-artery Repair: Model for Face and Scalp Transplantation.
    Date October 2003
    Journal Annals of Plastic Surgery
    Excerpt

    Successful replantation of the scalp with microanastomosis of a single artery and vein has been reported to produce reliable results. In fact, there have been several reports of scalp replantations based on one-artery and vein repair. There has been a face and scalp replantation reported in the literature, but this was as two separate parts and was based on several arterial and venous repairs. The authors performed the first successful replantation of a face and scalp with repair of a single artery and, of course, two veins. A 21-year-old man presented after his face and scalp were completely severed. The patient's long hair was caught in a conveyor belt at work. The face and scalp underwent replantation, with repair of the right superficial temporal artery with an interposition vein graft. A multiteam approach allowed for minimization of overall ischemic time and simultaneous preparation of the vessels on the patient and amputated part as well as vein graft harvest from the arm. Also critical to the success of the procedure, the small portions of the vessels of the amputated part were sent for frozen section to differentiate artery from vein. Initially, only the right superficial temporal vein was repaired. One week after replantation, the patient returned for treatment of venous congestion of an area to the opposite side of the forehead partial transection, with repair of the left superficial temporal vein, also. This saved the entire part that underwent replantation, and the entire part survived. The face and scalp can undergo replantation based on single-artery repair.

    Title Comparison of Two Leukapheresis Programs for Computerized Collection of Blood Progenitor Cells on a New Cell Separator.
    Date February 2003
    Journal Transfusion
    Excerpt

    Peripheral blood progenitor cells (PBPCs) can be collected on various cell separators. Two leukapheresis programs (LP-MNC and LP-PBSC-Lym) were evaluated for computerized collection of PBPCs on a new cell separator.

    Title Optimization of Cyanide Elimination from an Industrial Wastewater on a Pilot Plant Scale.
    Date November 2002
    Journal Annali Di Chimica
    Excerpt

    A pilot plant scale reactor was modelled and assembled to experimentally study the cyanide elimination process. The process was performed by using Ca(OCl)2, Cl2 and H2O2. The elimination was optimized at 25 degrees C for time of reaction, pH and amount of oxidant in a pilot plant scale reactor with synthetic solutions. Moreover some tests were carried out by using a real effluent deriving from a gold production industry.

    Title A New Dressing for Laser-treated Areas.
    Date September 2002
    Journal Plastic and Reconstructive Surgery
    Excerpt

    Contemporary studies and observations have left no doubt that occlusive dressings are superior to open treatment after laser resurfacing. The currently available occlusive dressings, however, are time-consuming to apply, often dislodge shortly after application, and most require reapplication. The authors report a cross-sectional observational study of patients who were treated with a new dual silicone-based dressing (DiamondSeal) after full-face laser resurfacing, with or without rhytidectomy. Patients who previously underwent similar surgeries and who were treated with a popular occlusive tape dressing (Flexzan) acted as historic controls. A combination of two silicones produced a gel-like silicone admixture that was spread evenly over the laser-treated areas. The silicone gel solidified into a flexible membrane and remained on the patient's face for 5 days. Questionnaires were sent to patients who were treated with the silicone dressing and those who were treated with a currently popular occlusive dressing. When the attributes of these dressings were compared, the superiority of the silicone dressing approached statistical significance ( = 0.08). The majority of patients treated with the silicone dressing (71 percent) had a positive experience with this dressing, stating they would repeat the experience if necessary. Only 54 percent of patients with a tape dressing were willing to repeat their experience ( = 0.18). The major advantages of this dressing, noted from the surgeon's perspective, were the speed with which the mask was applied; the ease of application, without the need for templates; the acceptable cure duration, allowing spontaneous contouring of the silicone along facial contours; the simple tailoring of the dressing; the reduced need for and minimal time for reapplication; and the paucity of complications.

    Title Ulcerative Eosinophilic Granuloma: a Report of Five New Cases.
    Date July 1996
    Journal The British Journal of Oral & Maxillofacial Surgery
    Excerpt

    Five new cases of ulcerative eosinophilic granuloma were diagnosed at the Massachusetts General Hospital between 1982 and 1993. In all cases the site was the tongue. They were unifocal, did not recur, and had a benign course. This report illustrates their benign nature despite the occasional aggressive presentation, and outlines possible aetiology.

    Title Frontonasal Suture Expansion in the Rabbit Using Titanium Screws.
    Date September 1995
    Journal Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
    Excerpt

    This study investigated the ability to use titanium screws to provide stable skeletal points in the growing craniofacial region of the rabbit for suture expansion. These screws provided sites for direct application of external forces to alter growth and anatomic form.

    Title Long-term Follow-up of Patients with Philadelphia Chromosome-positive Chronic Myeloid Leukemia After Stem Cell Mobilization Under Imatinib.
    Date
    Journal Leukemia & Lymphoma

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