Internists, Rheumatologist, Radiologist
22 years of experience

Spectrum Radiology
489 State St
Bangor, ME 04401
207-973-8150
Locations and availability (1)

Education ?

Medical School Score Rankings
Louisiana State University at Shreveport (1988)
  • Currently 3 of 4 apples
Top 50%

Awards & Distinctions ?

Associations
American Board of Internal Medicine
American Board of Radiology

Affiliations ?

Dr. Bryant is affiliated with 2 hospitals.

Hospital Affilations

Score

Rankings

  • St Joseph Hospital
    360 Broadway, Bangor, ME 04401
    • Currently 3 of 4 crosses
    Top 50%
  • Eastern Maine Medical Center
    489 State St, Bangor, ME 04401
    • Currently 2 of 4 crosses
  • Publications & Research

    Dr. Bryant has contributed to 118 publications.
    Title Colchicine for Prophylaxis of Acute Flares when Initiating Allopurinol for Chronic Gouty Arthritis.
    Date March 2005
    Journal The Journal of Rheumatology
    Excerpt

    OBJECTIVE: The use of colchicine to prevent acute gout flares during initiation of allopurinol therapy is widely practiced despite lack of proven benefit. We investigated if colchicine administration during initiation of allopurinol for chronic gouty arthritis reduces the frequency and/or severity of acute gout flares. METHODS: Patients starting allopurinol for crystal-proven chronic gouty arthritis were randomized to receive colchicine 0.6 mg po bid or placebo in a randomized, prospective, double blind, placebo controlled trial. Subjects were followed for evidence of acute gout flares and remained on study drug for 3 months beyond attaining a serum urate concentration < 6.5 mg/dl. Treatment arms were analyzed regarding frequency of flares, likelihood of any flare or multiple flares, severity of flares on the visual analog scale (VAS), and length of flares in days. RESULTS: Forty-three subjects were studied. Subjects treated with colchicine experienced fewer total flares (0.52 vs 2.91, p = 0.008), fewer flares from 0 to 3 months (0.57 vs 1.91, p = 0.022), fewer flares 3-6 months (0 vs 1.05, p = 0.033), less severe flares as reported on VAS (3.64 vs 5.08, p = 0.018), and fewer recurrent gout flares (p = 0.001). Colchicine was well tolerated. CONCLUSION: Colchicine prophylaxis during initiation of allopurinol for chronic gouty arthritis reduces the frequency and severity of acute flares, and reduces the likelihood of recurrent flares. Treating patients with colchicine during initiation of allopurinol therapy for 6 months is supported by our data.

    Title Clinical Images: Hydroxychloroquine-associated Mucocutaneous Hyperpigmentation.
    Date August 2002
    Journal Arthritis and Rheumatism
    Title Effect of Low Dose Daily Aspirin on Serum Urate Levels and Urinary Excretion in Patients Receiving Probenecid for Gouty Arthritis.
    Date February 2001
    Journal The Journal of Rheumatology
    Excerpt

    To determine if low dose daily enteric coated aspirin significantly affects the therapeutic actions of probenecid with respect to serum urate levels or urinary urate excretion.

    Title Hydroxychloroquine in the Treatment of Erosive Osteoarthritis.
    Date December 1995
    Journal The Journal of Rheumatology
    Excerpt

    Hydroxychloroquine has been used successfully in the treatment of inflammatory arthritides such as rheumatoid arthritis and systemic lupus erythematosus, and less commonly in the seronegative spondyloarthropathies. Our objective was to determine the effectiveness of hydroxy-chloroquine in inflammatory or erosive osteoarthritis (OA).

    Title Transfusion Medicine: the Pathologist's 'brave New World'.
    Date July 1989
    Journal American Journal of Clinical Pathology
    Title Aids in Louisiana. Blood Transfusions.
    Date January 1988
    Journal The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society
    Title Infections of the Lower Extremities Due to Gas-forming and Non-gas-forming Organisms.
    Date January 1987
    Journal Southern Medical Journal
    Excerpt

    From 1977 to 1984, 87 above- and below-knee amputations were done on 77 patients for ischemic ulcerations and gangrene of the lower extremities. The overall three-month mortality was 14% and was mainly related to generalized atherosclerosis. Patients having infections with gas formations were more likely to be diabetic (80% vs 15%, P less than .01), have clinical sepsis and a higher preoperative WBC (19,000 vs 12,600/cu mm, P less than .01), and have a higher mortality (40% vs 12%, P less than .05) than those with infections due to non-gas-forming organisms. Mixed bacterial flora were cultured from most wounds. We conclude that infections with gas formation may be due to either clostridial or nonclostridial organisms, mortality is higher if gas accumulates and if the patient is diabetic, gas is more likely to accumulate in infected extremities of diabetic patients, and the combination of gas formation and diabetes is highly lethal.

    Title Immune Responsiveness of Monkeys Exposed Chronically to Cigarette Smoke.
    Date September 1985
    Journal Clinical Immunology and Immunopathology
    Excerpt

    Eleven adult male stumptailed monkeys (Macaca arctoides) were chronically exposed to either a low dose (human equivalent of 1 pack/day) or a high dose (human equivalent of 3 packs/day) of high-tar, high-nicotine University of Kentucky reference cigarette smoke for 4-8 years. Several parameters of their immunological response were compared to six nonsmoked control animals. The results from these experiments suggest that cigarette smoking does not significantly affect the response of spleen cells to the mitogens phytohemagglutinin or lipopolysaccharide. However, spleen cells from animals subjected to the heavy dose of cigarette smoke demonstrated a significant reduction in their natural killer cell-mediated lytic activity and a decreased response to concanavalin A. These results suggest that cigarette smoking may have a differential effect on lymphocyte subpopulations, and that the effects on the immune response are related to the dose of cigarette smoke.

    Title Anti-tcb, an Antibody That Defines a Red Cell Antigen Antithetical to Tca.
    Date September 1985
    Journal Transfusion
    Excerpt

    A patient's serum, used as a source of anti-Goa typing serum, was found to contain a second antibody that detected a 'new' red cell antigen present in approximately 5 percent of blacks, but not yet found in Caucasians. Among blacks, the 'new' antigen shows an antithetical relationship to the high frequency antigen Tca, as evidenced by tests on eight unrelated Tc(a-) black women and the families of two of these propositi. The antigen, designated Tcb, has not been found on the red cells of Tc(a-) persons whose racial origins differ from the propositi of this report, which suggests that more than one genetic mechanism can produce the Tc(a-) phenotype. The presence of both anti-Goa and anti-Tcb in the same serum appears to be a coincidental and unrelated finding.

    Title The Safe Use of Cisplatin in Hyperthermic Isolated Limb Perfusion Systems.
    Date August 1985
    Journal Cancer
    Excerpt

    A patient presenting with aggressive squamous cell carcinoma successfully received cisplatin chemotherapy via hyperthermic, isolated limb perfusion (renal impairment ruled out systemic use). Human tumor stem cell assay identified cisplatin as the drug of choice and supports the potential benefit of this procedure in single therapeutic situations. The case illustrates the safety of cisplatin and the ability to give large doses of the nephrotoxic drug with no damage to renal function. The potential efficacy over systemic cisplatin has yet to be established except when systemic use is limited from renal dysfunction.

    Title Glutathione Status of Isolated Rabbit Lungs. Effects of Nitrofurantoin and Paraquat Perfusion with Normoxic and Hyperoxic Ventilation.
    Date May 1984
    Journal Biochemical Pharmacology
    Excerpt

    Thirty-minute perfusion of isolated rabbit lungs with a Krebs-Ringer bicarbonate buffer containing 420 microM paraquat (PQ) or nitrofurantoin (NF) resulted in increases in lung oxidized glutathione (GSSG) content of 589 and 2656%, respectively, over control levels. The degree of glutathione efflux was also increased with both agents, i.e. 77 and 238% above control leakage for PQ and NF respectively. The pulmonary toxicity of both compounds is known to be heightened by conditions of hyperoxia(O2). Ventilation of lungs with 95% O2-5% CO2 did not, in itself, significantly alter glutathione efflux, GSH or GSSG levels. However, ventilation with 95% O2-5% CO2 increased lung GSSG levels in PQ-perfused lungs 225% over PQ-air-perfused lungs, a combined effect not observed with NF-O2, wherein mean GSSG levels were only 72% of that observed with NF-air. Glutathione efflux in PQ-O2-treated lungs declined somewhat (20%) compared to that observed with PQ-air, but a significant increase in the amount of glutathione efflux was seen with NF-O2-treated lungs, i.e. 120 and 310%, respectively, over that attributable to NF or O2 alone. Although the biochemical mechanisms of toxicity of these compounds are thought to be very similar, the disparate degree of GSH oxidation observed with equimolar levels of PQ and NF may indicate differences in reactivity towards glutathione and other lung sulfhydryl pools. The stimulation of the oxidative effects of PQ and NF on lung GSH due to hyperoxic ventilation may be related to the reported O2 enhancement of their toxicity.

    Title Nifedipine for the Poor-risk Elderly Patient with Achalasia: Objective Response Demonstrated by Solid Meal Study.
    Date April 1984
    Journal Southern Medical Journal
    Excerpt

    We described an 84-year-old woman with symptomatic achalasia who refused both dilation and surgical treatment. She was treated with the calcium channel blocking drug nifedipine, with significant relief of symptoms. Objective evidence of response to the drug was confirmed by using an egg salad sandwich meal labeled with 99mTc-DTPA.

    Title Carnitine Metabolism in Macaca Arctoides: the Effects of Dietary Change and Fasting on Serum Triglycerides, Unesterified Carnitine, Esterified (acyl) Carnitine, and Beta-hydroxybutyrate.
    Date August 1982
    Journal The American Journal of Clinical Nutrition
    Excerpt

    Serum triglycerides and serum total, esterified, and free (unesterified) carnitine were measured in 21 male Macaca arctoides that were switched from a low fat (5.2% w/w), high carbohydrate diet to a high fat (15.9% w/w), low carbohydrate diet for 90 days and then returned to the original low fat diet for a subsequent 76-day period. Serum triglycerides and total carnitine levels fell significantly (p less than 0.05) during the initial 2 wk of feeding the high fat diet and the ratio of esterified/unesterified carnitine rose significantly (P less than 0.05) on the high fat diet. A return to the low fat diet reversed these changes; triglycerides rose significantly (p less than 0.05) within 3 days and the ratio of esterified/unesterified carnitine fell significantly (p less than 0.05) within 3 days and the ratio of esterified/unesterified carnitine fell significantly (p less than 0.05) during the same period. A return of total carnitine levels to those initially observed on the low fat diet was slower to develop. Fasting for 24 to 48 h resulted in increases of 65 to 75% in total serum carnitine. This increase reflected elevations of both the esterified and unesterified carnitine fractions but was largely attributable to increases in esterified carnitine which rose from 10 to 41 nmol/ml by 48 h while unesterified carnitine rose from 55 to 72 nmol/ml during the same period. In addition, the ratio of esterified/unesterified carnitine ratio rose from 0.183 +/- 0.023 to 0.583 +/- 0.069 (n = 8) with a 48-h fast and was significantly correlated with serum beta-hydroxybutyrate levels at both 24 and 48 h.

    Title Failure of Chronic Cigarette Smoke Exposure to Alter Plasma Lipoproteins of Stumptailed Macaques (macaca Arctoides).
    Date June 1982
    Journal Atherosclerosis
    Excerpt

    Twenty-one 8-14 kg adult male stumptailed macaques, Macaca arctoides, were fed a standard laboratory diet and divided into 3 groups. The high-dose group and low-dose group were exposed to cigarette smoke at the human equivalent of 3 packs and 1 pack per day, respectively, 7 days per week, for 3-5 years. Eight animals served as cage an sham controls. Peak blood carboxyhemoglobin (COHb) levels measured immediately after smoking showed levels of 0.5+/- 0.1%, 3.6+/-1.0%, and 5.7+/-2.8% for sham controls, low, and high dose smokers, respectively. Hemoglobin and hematocrit values were 2-7% higher (N.S. to P less than 0.05) for smoking groups, presumably as a consequence of chronically elevated COHb levels. No significant differences were seen in total plasma cholesterol and lipoprotein cholesterol concentration measured at four intervals over period of one year. We conclude from these data that, while fed a low fat diet, chronic cigarette smoke inhalation fails to alter plasma lipoprotein levels in this animal model.

    Title Effects of Nitrofurantoin on the Glutathione Redox Status and Related Enzymes in the Isolated, Perfused Rabbit Lung.
    Date March 1982
    Journal Research Communications in Chemical Pathology and Pharmacology
    Excerpt

    Nitrofurantoin (NF) is a urinary antimicrobial drug which causes pulmonary injury. We measured levels of total lung glutathione (TLG), a tripeptide central to cellular antioxidant defenses and xenobiotic detoxification, and enzyme activities related to maintenance and utilization of reduced glutathione (GSH) in isolated, New Zealand white rabbit lungs perfused with a Kreb's-Ringer's bicarbonate medium containing NF (420 microM). After 30 minutes there was no net difference in the level of TLG [GSH + GSSG(oxidized) + effluent GSH-GSSG] or total nonprotein sulfhydryls in NF-perfused or control lungs. However, there was a decrease in the GSH:GSSG redox ratio to 2% of control (P less than .0005) and an 87% increase in GSH-GSSG efflux (P less than .005). This increased oxidation of GSH indicates that toxicity of NF is likely oxidative in nature, possibly via redox cycling of NF in the presence of oxygen to generate activated oxygen species. Activities of glucose-6-phosphate and 6-phosphogluconate dehydrogenases, GSH reductase, and GSH S-transferase were not significantly different due to NF perfusion. GSH peroxidase activity decreased 34% (P less than .025) in NF-perfused lungs. Because all TLG, as well as total nonprotein thiol was accounted for in NF-perfused lungs, it would appear that no GSH-NF metabolite conjugation occurred. GSH metabolic conjugation in the perfused lung is easily detected when tissue-alkylating drugs or their metabolites are present.

    Title Preservation of an Infected Arterial Graft with Combination Systemic-topical Antibiotic Therapy.
    Date January 1982
    Journal The American Surgeon
    Excerpt

    A case is presented which illustrates the unusual ability to retain a bifurcation aortofemoral vascular graft with the graft-to-femoral-artery anastomosis involved in a groin abscess. The drainage of the abscess, debridement of devitalized tissue, and the combined application of topical and systemic antibiotic therapy was successful. Some authors report that should an anastomosis of a bifurcation vascular graft, in the vicinity of the groin, become involved in infection, the threat of anastomotic disruption and continued sepsis may lead to amputation, death, or both. It is not the purpose of this report to advocate conservative management of a vascular graft infection with suture line involvement based on anecdotal experience. However, the case reported here and the experience of other authors mentioned suggest that an attempt to treat an infected graft without its removal may be indicated in selected patients where extra anatomical revascularization would be hazardous.

    Title Cardiac Tamponade Following Penetrating Mediastinal Injuries: Improved Survival with Early Pericardiocentesis.
    Date August 1979
    Journal The Journal of Trauma
    Excerpt

    Cardiac tamponade was diagnosed in 197 patients admitted over 20 years (1955-1974) to the Charity Hospital of New Orleans, for emergency treatment of pentrating mediastinal injuries. Of the 197, 174 definitively treated patients followed one of three patterns of management: 96 had OR thoracotomy, 68% were unstable, and preoperative pericardiocentesis reduced mortality from 25 to 11% (p less than 0.01); 44 had emergency thoracotomy, 91% were unstable, and prethoractomy pericardiocentesis decreased mortality from 94 to 63% (p less than 0.05); 34 patients primarily with isolated stab wounds, were treated nonsurgically with pericardiocentesis and observation, only 50% were unstable and there was 15% mortality. Recurrent tamponade did not significantly increase overall or operative mortality in patients with pericardiocentesis. Recommendations: early, even presumptive, diagnosis of tamponade; immediate pericardial decompression via pericardiocentesis; and rapid transfer to OR for thoracotomy or sternotomy and cardiorrhaphy with continous pericardial decompression via intrapericardial catheter.

    Title Bilateral Apical Intrathoracic Masses Associated with Von Recklinghausen's Disease.
    Date May 1979
    Journal Chest
    Title Optimal Leukocyte Removal from Refrigerated Blood with the Ibm 2991 Blood Cell Processor.
    Date October 1978
    Journal Transfusion
    Excerpt

    One hundred forty-six units of two to five-day-old refrigerated blood were washed with the IBM Blood Cell Processor. The ABO and Rh types of the units varied according to available inventory. This study was designed to select the best protocol from the 42 possible combinations utilizing the machine's variable red blood cell override (RCO). A one liter wash program was used. The two parameters selected for study were the per cent red blood cell recovery and the per cent white blood cell removal. The protocol of choice uses a RCO of four seconds in the first and second steps of the program. This protocol yields a washed unit with a mean red blood cell recovery of 82 per cent and a mean white cell removal of 93 per cent. Our studies indicate that the IBM Blood Cell Processor can be used to wash two to five day old refrigerated blood for the preparation of leukocyte-poor blood that would meet the Standards of the AABB.

    Title Bilateral Diaphragmatic Rupture Due to Blunt Trauma--a Rare Injury.
    Date August 1978
    Journal The Journal of Trauma
    Excerpt

    A young male patient with bilateral rupture of the diaphragm due to blunt trauma is presented. A separate tear occurred in each hemidiaphragm but recognition and repair of the right side was delayed. After healing of other injuries successful operation was performed 55 days postinjury by a transthoracic approach.

    Title A Proposed Technique for Treatment of Hypoplastic Left Heart Syndrome.
    Date August 1978
    Journal The Journal of Cardiovascular Surgery
    Excerpt

    The Hypoplastic Left Heart Syndrome includes a variety of anomalies, all characterized by a hypoplastic or absent left ventricle. A technique is described for producing a normal course of circulation in these cases. Its ultimate success will depend on the patients having a low pulmonary vascular resistence.

    Title "general" Versus "noncardiac" Thoracic Surgery.
    Date June 1978
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Evaluation of Tracheal Incisions for Tracheostomy.
    Date June 1978
    Journal American Journal of Surgery
    Excerpt

    Three standard tracheostomy incisions in dogs were compared to determine whether any were more likely associated with stomal stenosis. Each incision resulted in an average reduction in tracheal lumen of 25 per cent, with a 50 per cent maximum. The incision selected should depend on the conditions present.

    Title Localization of Bronchogenic Carcinoma in Tuberculous Lobes.
    Date May 1978
    Journal Southern Medical Journal
    Excerpt

    The pronounced predilection of bronchogenic carcinoma for tuberculous lobes of the lungs is not generally recognized. In this plus 11 other series of patients with coexisting disease, an average of 52% had the neoplasm in a tuberculous lobe. In the present study, tuberculosis was confined to one or two lobes in 24 of 27 patients (89%) with coexisting disease; 21 (88%) of these patients had the neoplasm in a tuberculous lobe. Diagnosis required an average of 1.8 months (one week to 18 months). A low index of suspicion can delay diagnosis of the carcinoma until hilar enlargement, tumor, or metastasis is apparent radiologically, By then, often the tumor has become inoperable. Our data suggest that carcinoma should be suspected in a tuberculous man of cancer age who smokes and who has a lesion which is enlarging, is in an unusual location, or is drug resistant. Cytologic study of sputum, bronchoscopy, and early thoractomy are advocated.

    Title The Large Scale Use of Frozen Blood by the Hospital Blood Bank.
    Date September 1977
    Journal The American Journal of Medical Technology
    Excerpt

    The large scale use of frozen blood has become practical and economical. Inventory control can be mastered. Components are derived as a by-product. An autologous blood transfusion program can be successfully developed. Frozen blood is available for transplantation patients. tover 25,000 units of frozen-thawed erythrocytes have been given without an allergic, anaphylactoid, or febrile reaction. In the future the majority of red blood cell transfusions may be given as frozen-thawed erythrocytes supplemented by washed refrigerated blood with optimal 2,3 DPG levels.

    Title Seven Year Experience with Mounted Porcine Valves.
    Date June 1977
    Journal Annals of Surgery
    Excerpt

    From March, 1969, through June 1976, 108 porcine aortic xenograft valves were used for mitral or aortic valve replacement in 95 patients. This experience provides one of the longest follow-ups available for evaluation of the porcine bioprosthesis. The first fifteen valves were locally mounted on Cutter stents and preserved in buffered formalin. Subsequent valves were prepared by the Edwards and Hancock Companies with glutaraldehyde preservation. Oral anticoagulation was routinely used for the first 6 weeks following surgery. Hospital mortality was unrelated to the valve type. All but four of the surviving patients with formalin preserved valves have required reoperation because of valve failure. There have been two valve failures in the patients who received gluteraldehyde valves, but there have been no embolic or thrombotic complications. Late cardiac catheterization has shown hemodynamic results equal to or better than prosthetic valves. The continuing long-term results indicate that the porcine xenograft is the valve of choice for cardiac valve replacement.

    Title Fell Tube Insertion After Orthograde Dilatation of Malignant Esophageal Obstruction: Palliation and Morbidity.
    Date May 1977
    Journal Southern Medical Journal
    Excerpt

    Twenty-eight patients with malignant esophageal obstruction had palliative treatment using the Fell endoesophageal tube. The usual plan for these patients, irradiation followed by resection, was not followed because of the presence of tracheoesophageal fistula, celiac or hepatic metastases, or marked debilitation which precluded major operation. Palliation was obtained in ten patients who were discharged in a mean of 16.5 days with the ability to swallow liquids or pureed or ground foods and had a mean survival of 116 days. There was a high incidence of tube-related symptoms in all patients, and increased dysphagia, tube regurgitation, and difficulties in initiating swallowing were noted in patients with lesions above 24 cm from the incisors. The high incidence of postoperative ocmplications was responsible for the poor palliation and low survival in the remaining 18 patients who had a mean survival of 41 days. It was concluded that orthograde dilatation or forced seating of the prosthesis through a malignant esophageal obstruction carries a significant risk of perforation of the esophagus which, if it occurs, negates the palliative aspects of the procedure, increases hospitalization, and decreases survival. It is recommended that this procedure be used selectively in patients not otherwise amenable to resectional therapy with lesions beyond 24 cm from the incisors.

    Title Hospital-based Program Shows Advantages of Using Frozen Blood.
    Date October 1976
    Journal Hospitals
    Title Editorial: Performance Standards for Tracheal Tubes and Cuffs.
    Date June 1976
    Journal The Annals of Thoracic Surgery
    Title Pleural Flap Closure of Pericardial Defects Following Intrapericardial Pneumonectomy.
    Date March 1976
    Journal The Annals of Thoracic Surgery
    Excerpt

    Persistent pericardial defects following intrapericardial pneumonectomy are, historically, the major cause of iatrogenic cardiac herniation. This complication is uniformly fatal when unrecognized and untreated and has been associated with a 43% mortality even with surgical correction. Suture approximation of all small defects is recommended, and a technique for routine pleural flap closure of moderate to large-sized defects is described.

    Title Effects of Hypercalcemia on Subendocardial Perfusion and Ventricular Wall During Cardiopulmonary Bypass.
    Date October 1975
    Journal Surgical Forum
    Title Prophylactic Antibiotics in Noncardiac Thoracic Operations.
    Date September 1975
    Journal The Annals of Thoracic Surgery
    Excerpt

    A high incidence of thoracotomy wound infection and empyema in 1972 was associated with inadequate and irregular administration of prophylactic antibiotics. Beginning with 1973, a strict regimen was adopted that combined systemic cephalosporins and two topical antibiotics (cephalothin and kanamycin). Emphasis was placed on preoperative administration of the systemic agent and on use of the topical drugs before the operative field was contaminated. The patient groups for 1972 and 1973 were similar in most respects, but the wound complication rate was 18.4% in 1972 and 4.8% in 1973.

    Title The Inferior Vena Cava Umbrella Filter.
    Date July 1975
    Journal Progress in Cardiovascular Diseases
    Title Restraining Chair and Face Mask for Inhalation Toxicology Studies in Primates.
    Date May 1975
    Journal Journal of Medical Primatology
    Title Hemodynamic Selection of Patients with Bacterial Endocarditis for Valve Replacement.
    Date March 1975
    Journal Bulletin De La Société Internationale De Chirurgie
    Title Experiences with Frozen Erythrocytes in a Private Hospital.
    Date December 1974
    Journal Transfusion
    Title Subendocardial Vascular Distortion at Small Ventricular Volumes.
    Date November 1974
    Journal The Journal of Surgical Research
    Title What is Rational Treatment for Carcinoma of the Esophagus and Cardia?
    Date September 1974
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Massive Pulmonary Embolism: a Plan of Medical Management.
    Date August 1974
    Journal Southern Medical Journal
    Title Determinants of Myocardial Water Content During Cardiopulmonary Bypass.
    Date August 1974
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Experimental and Clinical Evaluation of Heparin-impregnated Cloth-covered Cardiac Valves Used Without Systemic Anticoagulation.
    Date May 1974
    Journal The Annals of Thoracic Surgery
    Title Pulmonary Contusion. Pathogenesis and Effect of Various Resuscitative Measures.
    Date January 1974
    Journal The Annals of Thoracic Surgery
    Title Screening of Blood Donors for Hepatitis-associated Antigen and Antibody.
    Date December 1973
    Journal American Journal of Clinical Pathology
    Title Further Evaluation of Inferior Vena Cava Umbrella-filter.
    Date October 1973
    Journal Bulletin De La Société Internationale De Chirurgie
    Title Cardiac Valve Injury with Major Chest Trauma.
    Date September 1973
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title The Metabolic Effect of Fluoride Inhibition of Anaerobic Glycolysis During Hemorrhagic Shock.
    Date September 1973
    Journal The Journal of Surgical Research
    Title Recurrent Benign Fibrous Mesothelioma of the Pleura.
    Date June 1973
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Right Ventricular Mesothelioma with Pulmonary Obstruction.
    Date June 1973
    Journal Chest
    Title Misdiagnosis of Pneumonia in Patients Needing Mechanical Respiration.
    Date May 1973
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Interpretation of Tracheal Cultures in Patients with Intubation and Mechanical Ventilation.
    Date April 1973
    Journal The American Surgeon
    Title Comparison of Ice Water with Iced Saline Solution for Gastric Lavage in Gastroduodenal Hemorrhage.
    Date January 1973
    Journal American Journal of Surgery
    Title Deep Hypothermia and Circulatory Arrest Induced by Left Ventricular Bypass.
    Date September 1972
    Journal The Journal of Surgical Research
    Title Infected Permanent Cardiac Pacemaker. Management Without Removal.
    Date September 1972
    Journal The Annals of Thoracic Surgery
    Title Bacterial Colonization Profile with Tracheal Intubation and Mechanical Ventilation.
    Date July 1972
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Transit Time and Bacterial Overgrowth As Determinants of Absorptive Capacity.
    Date June 1972
    Journal The Journal of Surgical Research
    Title Surgical Approach for Posterior Ventricular Aneurysm.
    Date June 1972
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Limitations of Lung Scintiscanning in Pulmonary Transplantation.
    Date May 1972
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Myocardial Infarctectomy and Repair of Ruptured Ventricular Septum During Acute Stage of Infarction.
    Date April 1972
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Lung Perfusion Scanning for Estimation of Postoperative Pulmonary Function.
    Date March 1972
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Present Status of the Inferior Vena Cava Umbrella Filter.
    Date February 1972
    Journal Surgery
    Title A New Concept in Tracheostomy Balloon Cuffs.
    Date January 1972
    Journal Surgical Forum
    Title Surgery for Coronary Artery.
    Date January 1972
    Journal The Journal of the Kentucky Medical Association
    Title Circulatory Arrest During Deep Hypothermia Induced by Peritoneal Dialysis.
    Date January 1972
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Cytologic Features of Pericardial Mesothelium.
    Date October 1971
    Journal Acta Cytologica
    Title Primary Anastomosis of Aneurysms of the Ascending Aorta Caused by Cystic Medial Necrosis.
    Date September 1971
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title A Two-point Hook for Mitral Valve Excision.
    Date August 1971
    Journal The Annals of Thoracic Surgery
    Title Tracheo-bronchial Collapsibility, an In-vivo and Ex-vivo Study.
    Date July 1971
    Journal Respiration; International Review of Thoracic Diseases
    Title Mitral Valvotomy in the Valve Replacement Era.
    Date July 1971
    Journal Annals of Surgery
    Title Cardiac Valve Replacement in Patients with Severely Reduced Cardiac Output.
    Date July 1971
    Journal The Annals of Thoracic Surgery
    Title Cardiac Valve Replacement. Results in Patients with Advanced Disability.
    Date June 1971
    Journal Jama : the Journal of the American Medical Association
    Title A Simple Modification of Existing Respirators to Provide Constant Positive-pressure Breathing.
    Date May 1971
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title A Technique for Intercostal Nerve Block After Thoracotomy.
    Date May 1971
    Journal The Annals of Thoracic Surgery
    Title Reappraisal of Tracheal Injury from Cuffed Tracheostomy Tubes. Experiments in Dogs.
    Date March 1971
    Journal Jama : the Journal of the American Medical Association
    Title Mechanical Support of the Circulation: a New Approach.
    Date February 1971
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Pulsatile Cardiopulmonary Bypass: Clinical Evaluation.
    Date January 1971
    Journal Surgery
    Title Acute Respiratory Pathophysiology After Hemorrhagic Shock.
    Date November 1970
    Journal Surgery
    Title Appendicitis and Appendiceal Perforation in Neonates.
    Date November 1970
    Journal The American Surgeon
    Title Mediastinoscopy--experience with 300 Consecutive Cases.
    Date October 1970
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Present-day Risk of Thoracotomy in Patients with Compromised Pulmonary Function.
    Date October 1970
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Intermittent Positive-pressure Breathing.
    Date September 1970
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Pericardiectomy for Constrictive Pericarditis.
    Date July 1970
    Journal Southern Medical Journal
    Title Surgical Management of Gastroschisis.
    Date July 1970
    Journal Annals of Surgery
    Title Use of Pluronic F-68 to Diminish Fat Emboli and Hemolysis During Cardiopulmonary Bypass. A Controlled Clinical Study.
    Date July 1970
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Metabolic Comparison of a New Pulsatile Pump and a Roller Pump for Cardiopulmonary Bypass.
    Date December 1969
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Emergency Operation for Cyanotic Heart Disease in Infants.
    Date August 1969
    Journal The Journal of the Kentucky Medical Association
    Title Treatment of Median Sternotomy Infection by Mediastinal Irrigation with an Antibiotic Solution.
    Date July 1969
    Journal Annals of Surgery
    Title What's New in Prosthetic Heart Valves.
    Date June 1969
    Journal The Journal of the Kentucky Medical Association
    Title The Operative Management of Idiopathic Mesenteric Venous Thrombosis with Intestinal Infarction.
    Date June 1969
    Journal The American Surgeon
    Title Distribution of Pulmonary Bloodflow in Chronic Airways Obstruction: Lung Scintiscanning and Pulmonary Arteriography.
    Date January 1969
    Journal Aspen Emphysema Conference
    Title Aneurysms of the Ascending Aorta with Aortic Valve Incompetence.
    Date December 1968
    Journal The Journal of the Kentucky Medical Association
    Title Mediastinoscopy--diagnostic Value Compared to Bronchoscopy: Scalene Biopsy and Sputum Cytology in 155 Patients.
    Date November 1968
    Journal The American Surgeon
    Title Ampullary Obstruction by Benign Duodenal Polyps.
    Date October 1968
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Thoracic Aneurysms with Aortico-bronchial Fistula.
    Date October 1968
    Journal Annals of Surgery
    Title Permanent Cardiac Pacemakers. Thoracotomy Versus Transvenous Implantation.
    Date October 1968
    Journal The Journal of the Kentucky Medical Association
    Title Pathogenesis of Cutaneous Lesions of Actinomycosis.
    Date October 1968
    Journal Southern Medical Journal
    Title Influence of Thoracotomy and Intrathoracic Dissection on Regional Pulmonary Blood Flow.
    Date September 1968
    Journal The Journal of Surgical Research
    Title Cardiac Growth Following Atrial Replacement with Prosthetic Materials.
    Date July 1968
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Management of Thoracic Empyema.
    Date July 1968
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Cannulation Under Local or Regional Anesthesia for the "salvage" Cardiac Patient.
    Date July 1968
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Pulmonary Blood Flow Distribution in Chronic Obstructive Airway Disease. Lung Scintiscanning and Pulmonary Arteriography.
    Date June 1968
    Journal The American Review of Respiratory Disease
    Title Histiocytoma (fibrous Xanthoma) of the Lung.
    Date May 1968
    Journal American Journal of Surgery
    Title Pulmonary Parenchymal Spread of Juvenile Laryngeal Papillomatosis.
    Date May 1968
    Journal Radiology
    Title Reversed Colon Segment in an Infant with Massive Small Bowel Resection: a Case Report.
    Date April 1968
    Journal The Journal of the Kentucky Medical Association
    Title Tolerance to Prolonged Cross Circulation in Dogs.
    Date January 1968
    Journal American Journal of Surgery
    Title Pacemaker Therapy in Complete Heart Block: Current Concepts of Management.
    Date October 1967
    Journal The Journal of the Kentucky Medical Association
    Title Failure of Endocardial Pacemaker Due to Late Myocardial Perforation. Successful Restoration of Cardiac Pacing by Conversion to an Epicardial System.
    Date September 1967
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Prolonged Cross-circulation for Reversible Pulmonary Failure.
    Date August 1967
    Journal Surgery
    Title Epilepsy Induced by Cardiac Pacemaker.
    Date June 1967
    Journal Jama : the Journal of the American Medical Association
    Title Parabiotic Resuscitation in Profound Cardiovascular Failure. Experimental Results in Canine Hemorrhagic Shock.
    Date April 1967
    Journal Jama : the Journal of the American Medical Association
    Title Mechanical Respirators. Their Use and Application in Lung Trauma.
    Date March 1967
    Journal Jama : the Journal of the American Medical Association
    Title Postoperative Changes in Regional Pulmonary Blood Flow.
    Date March 1967
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Parabiotic Resuscitation in Irreversible Hemorrhagic Shock.
    Date January 1967
    Journal Surgical Forum
    Title Cystoscope Endoscopy in the H-type Tracheoesophageal Fistula.
    Date November 1966
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Vagotomy and Pyloroplasty. An Inadequate Operation for Stress Ulcers?
    Date August 1966
    Journal Archives of Surgery (chicago, Ill. : 1960)
    Title Occlusive Disease of Subclavian Artery.
    Date June 1966
    Journal Jama : the Journal of the American Medical Association
    Title Experimental Evaluation of Intercostal Pedicle Grafts in Esophageal Repair.
    Date February 1966
    Journal The Journal of Thoracic and Cardiovascular Surgery
    Title Comparison of Planar Scintigraphy Alone and with Spect for the Initial Evaluation of Femoral Neck Stress Fracture.
    Date
    Journal Ajr. American Journal of Roentgenology
    Excerpt

    OBJECTIVE: The objective of our study was to compare the accuracy of planar scintigraphy alone versus planar scintigraphy with SPECT for the initial evaluation of femoral neck stress fractures in a young military population. MATERIALS AND METHODS: We retrospectively identified 38 patients who had undergone planar scintigraphy and 33 patients who had undergone planar scintigraphy and SPECT before MRI of the hips over a 6-month period for evaluation of suspected femoral neck fracture. Data were analyzed regarding the sensitivity and specificity of bone scanning alone and with SPECT for detecting femoral neck stress fracture and grading fractures as low grade (grades I and II) or high grade (grades III and IV). RESULTS: Twelve fractures were identified in the group who underwent planar scintigraphy alone and 13 in the group who underwent planar scintigraphy with SPECT. The sensitivities of planar scintigraphy alone and with SPECT were 50% and 92.3%, respectively (p = 0.03). The accuracy of each technique for the detection of high-grade fractures was 12.5% and 70%, respectively (p = 0.025). CONCLUSION: Planar scintigraphy with SPECT had a higher sensitivity and accuracy in assessing the grade of femoral neck stress fractures than planar scintigraphy alone. The results of this study suggest that SPECT should be performed with planar bone scintigraphy for the evaluation of patients with suspected femoral neck stress fractures.

    Title Onset of Erosive Osteoarthritis in a Teenage Girl.
    Date
    Journal Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases
    Excerpt

    Erosive osteoarthritis is a disorder that predominantly affects the hands of postmenopausal or middle aged women. Ages usually range from 30 to 83 years. Although the etiology of erosive osteoarthritis is not known, a lack of estrogen hormones has been implicated in the pathogenesis. We report a patient with onset of symptoms at age 16 and a diagnosis at age 21. She has aggressive inflammatory involvement of the distal interphalangeal joints and characteristic radiographic changes with central erosions. She is not postmenopausal nor does she have any conditions that are believed to be possible associations with erosive osteoarthritis. To the best of our knowledge, this is the youngest reported patient with erosive osteoarthritis in the literature.


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