Browse Health


Education ?

Medical School
American University of the Caribbean (1984)

Awards & Distinctions ?

Hour Detroit Magazine's TOP DOCS+
Patients' Choice Award (2008 - 2011, 2014)
Compassionate Doctor Recognition (2010 - 2011, 2014)
On-Time Doctor Award (2014)
American Board of Preventive Medicine

Affiliations ?

Dr. Harbut is affiliated with 8 hospitals.

Hospital Affiliations



  • Providence Hospital and Medical Center
    16001 W 9 Mile Rd, Southfield, MI 48075
    Top 25%
  • DMC - Sinai-Grace Hospital
    6071 W Outer Dr, Detroit, MI 48235
    Top 25%
  • Harper University Hospital
    3990 John R St, Detroit, MI 48201
    Top 50%
  • St John Detroit Riverview Hospital
    7733 E Jefferson Ave, Detroit, MI 48214
    Top 50%
  • St. John Macomb-Oakland Hospital (Oakland Center)
    27351 Dequindre Rd, Madison Heights, MI 48071
    Top 50%
  • Detroit Receiving Hospital & University Health Center
    4201 Saint Antoine St, Detroit, MI 48201
    Top 50%
  • Providence Park Hospital
    47601 Grand River Ave, Novi, MI 48374
  • Karmanos Cancer Center
    4100 John R St, Detroit, MI 48201
  • Publications & Research

    Dr. Harbut has contributed to 7 publications.
    Title New Insight into the Molecular Mechanisms of the Biological Effects of Dna Minor Groove Binders.
    Date February 2012
    Journal Plos One

    Bisbenzimides, or Hoechst 33258 (H258), and its derivative Hoechst 33342 (H342) are archetypal molecules for designing minor groove binders, and widely used as tools for staining DNA and analyzing side population cells. They are supravital DNA minor groove binders with AT selectivity. H342 and H258 share similar biological effects based on the similarity of their chemical structures, but also have their unique biological effects. For example, H342, but not H258, is a potent apoptotic inducer and both H342 and H258 can induce transgene overexpression in in vitro studies. However, the molecular mechanisms by which Hoechst dyes induce apoptosis and enhance transgene overexpression are unclear.

    Title Clinical Presentation of Asbestosis with Intractable Pleural Pain in the Adult Child of a Taconite Miner and Radiographic Demonstration of the Probable Pathology Causing the Pain.
    Date September 2009
    Journal International Journal of Occupational and Environmental Health

    Taconite, although not classified by the United States Government as asbestos or asbestiform material, has been associated with asbestos-related diseases. The mineral is used in the production of steel and as a road-patch material and is mined in Michigan and Minnesota. This report describes the case of a middle-aged Caucasian woman with exposure to taconite mining dust from her miner father's clothing in childhood with a resultant presentation consistent with asbestosis and intractable pleural pain. Intractable pleural pain has been described in asbestos-exposed patients with theorized etiologies. However, no in vivo reported mechanism has demonstrated a plausible, anatomically apparent mechanism for the pain. We utilize an application of the Vitrea software for enhancement of high-resolution computerized tomography which demonstrates at least one likely mechanism for intractable pleural pain.

    Title Treatment of Nonmalignant Asbestos-related Diseases.
    Date February 2007
    Journal American Journal of Industrial Medicine
    Title Comparison of B Readers' Interpretations of Chest Radiographs for Asbestos Related Changes.
    Date April 2005
    Journal Academic Radiology
    Title Biomarkers for Establishing a Relationship Between Disease and Exposure.
    Date February 2002
    Journal Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine
    Title Arsenic Body Burden and Morbidity and Mortality.
    Date September 2001
    Journal Archives of Environmental Health
    Title Respiratory Health in Asbestos-exposed Ironworkers.
    Date September 1996
    Journal American Journal of Industrial Medicine

    This study aimed to determine the prevalence of respiratory morbidity among asbestos-exposed ironworkers and to determine the relationship between respiratory morbidity indices and length of exposure. A medical screening provided information on chest radiographic abnormalities, pulmonary function, rales, finger clubbing, and respiratory symptoms for 547 asbestos-exposed ironworkers. Union pension records furnished data on length of exposure. The study group exhibited on increased prevalence of small irregular opacities, pleural plaques, and pleural thickening on chest x-ray; reduced FEF 25-75; rales; and respiratory symptoms. After controlling for the effect of cigarette smoking and age, years since joining the ironworkers union were significantly associated with profusion, pleural thickening, pleural plaques, rales, percent predicted FVC, reduced FVC, reduced FEV1, reduced FEV1/FVC, and dyspnea grades I, II, III, and IV.

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