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Dr. Ingle is affiliated with 1 hospitals.

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  • Providence Alaska Medical Center
    PO Box 196604, Anchorage, AK 99519
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  • Publications & Research

    Dr. Ingle has contributed to 2 publications.
    Title The Natural History of Perianal Crohn's Disease.
    Date January 2008
    Journal Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
    Excerpt

    Perianal lesions are exceedingly common in Crohn's disease and many patients have more than one type of lesion. Skin tags, fissures and haemorrhoids may persist over time and are usually managed expectantly or with topical therapy. Perianal and rectovaginal fistulas and associated abscesses often require both local and systemic therapy, and recurrence is common. In general, the clinical course of Crohn's disease is more aggressive in patients with perianal involvement. Established risk factors for perianal disease include colonic disease and young age at disease onset. Classification schema now recognize perianal fistulas as distinct from other forms of penetrating Crohn's disease. Genetic susceptibility factors for perianal disease may exist, but they remain incompletely delineated at present. There is hope that immunosuppressive and biotechnology medications will influence the natural history of perianal disease by preventing invasive surgeries, disease complications and recurrence, but this needs to be confirmed. Cancer, a rare complication of perianal disease, must be suspected when lesions persist despite therapy.

    Title Can Selenium Supplementation Prevent Colorectal Cancer?
    Date December 2006
    Journal Gastroenterology

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