Anesthesiologist (pain control), Emergency Physician, Pediatricians
31 years of experience

North Campus
University of New Mexico
2211 Lomas Blvd NE
Albuquerque, NM 87106
505-272-2610
Locations and availability (2)

Education ?

Medical School Score Rankings
University of Washington (1979)
  • Currently 4 of 4 apples
Top 25%

Awards & Distinctions ?

Appointments
University of Cincinnatti
Assoc Professor Emeritus
Associations
American Board of Pediatrics
American Board of Anesthesiology

Affiliations ?

Dr. Long is affiliated with 1 hospitals.

Hospital Affilations

Score

Rankings

  • University of New Mexico Hospital
    2211 Lomas Blvd NE, Albuquerque, NM 87106
    • Currently 1 of 4 crosses
  • Publications & Research

    Dr. Long has contributed to 14 publications.
    Title Degradable, Thermo-sensitive Poly(n-isopropyl Acrylamide)-based Scaffolds with Controlled Porosity for Tissue Engineering Applications.
    Date February 2011
    Journal Biomacromolecules
    Excerpt

    We have developed a thermoresponsive poly(N-isopropyl acrylamide)-based scaffold with degradability and controlled porosity. Biodegradable poly(N-isopropyl acrylamide) hydrogels were synthesized by photocopolymerization of N-isopropylacrylamide with 2-methylene-1,3-dioxepane and polycaprolactone dimethacrylate. The hydrogels' phase transition temperature, swelling, and viscoelastic properties, as well as hydrolytic degradability at 25 and 37 °C, were explored. A sphere-templating technique was applied to fabricate hydrogel scaffolds with controllable pore size and a highly interconnected porous structure. The scaffold pore diameter change as a function of temperature was evaluated and, as expected, pores decreased in diameter when the temperature was raised to 37 °C. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test results suggested neither the scaffolds nor their degradation products were cytotoxic to NIH3T3 cells. Scaffolds with 55 ± 5 μm pore diameter were loaded with NIH3T3 cells and then were warmed to 37 °C entrapping cells in pores approximately 39 μm in diameter, a size range we have found to be optimal for angiogenesis and biointegration. Cells showed uniform infiltration and an elongated morphology after 7 days of culture. Due to the controlled monodisperse pore diameter, highly interconnected architecture, fully degradable chemistry and thermoresponsive properties, the polyNIPAM-based scaffolds developed here are attractive for applications in tissue engineering.

    Title Transfusing Platelets 2 H After the Completion of Amphotericin-b Decreases Its Detrimental Effect on Transfused Platelet Recovery and Survival.
    Date June 1998
    Journal Transfusion Medicine (oxford, England)
    Excerpt

    Platelet transfusion support is required during bone marrow aplasia following ablative chemotherapy and bone marrow progenitor cell transplantation (BMT). Amphotericin-B is frequently given to these patients, both therapeutically and prophylactically, and has been described to have a negative impact on the results of platelet transfusions. We conducted a prospective study of the effect of amphotericin-B on transfused platelet recovery and survival in 81 BMT or acute leukaemia patients. One hundred and ninety-five platelet transfusions administered to 81 consecutive patients were analysed. The platelets were transfused 2 h after the completion of amphotericin-B. Using this schedule resulted in no effect of amphotericin-B on platelet recovery or survival, although platelet increments were modestly depressed in patients receiving high- vs. low-dose amphotericin-B. We conclude that the timing of amphotericin-B infusion be evaluated in patients demonstrating poor platelet recovery and survival. Transfusing platelets at least 2 h after the completion of amphotericin-B decreases the detrimental effect of this antifungal agent on transfused platelet recovery and survival.

    Title An Evaluation of the Genotoxic Potential of Glyphosate.
    Date July 1988
    Journal Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology
    Excerpt

    The potential genotoxicity of glyphosate, the active ingredient in Roundup herbicide, was tested in a variety of well-established in vitro and in vivo assays including the Salmonella typhimurium and Escherichia coli WP-2 reversion assays, recombination (rec-assay) with Bacillus subtilis. Chinese hamster ovary cell gene mutation assay at the hypoxanthine/guanine phosphoribosyl transferase gene locus, hepatocyte primary culture/DNA repair assay, and in vivo cytogenetics assay in rat bone marrow. No genotoxic activity was observed in the assays performed. The data suggest that glyphosate should not pose a genetic risk to man.

    Title Acute Toxicity of Roundup and Rodeo Herbicides to Rainbow Trout, Chinook, and Coho Salmon.
    Date April 1988
    Journal Bulletin of Environmental Contamination and Toxicology
    Title Coccidioidomycosis in Adolescents Presenting As Chest Pain.
    Date September 1987
    Journal Journal of Adolescent Health Care : Official Publication of the Society for Adolescent Medicine
    Excerpt

    Chest pain is a relatively common complaint in adolescents and is most often attributed to anxiety or musculoskeletal conditions. Pleuritic chest pain in association with fever and cough are frequently reported in adults with primary pulmonary coccidioidomycosis. We describe three cases in which chest pain mimicking costochondritis was the predominant initial presenting symptom of pulmonary coccidioidomycosis. In addition, in each case, recent tuberculin skin test reactivity complicated the diagnostic assessment and treatment. We conclude that, in endemic areas, coccidioidomycosis should be considered in the differential diagnosis of acute chest pain in teenagers as well as in adults.

    Title Anorexia Nervosa.
    Date May 1987
    Journal Primary Care
    Excerpt

    Anorexia nervosa is a complex neuroendocrine-psychiatric illness that affects adolescents; its origins and pathophysiology are still poorly understood. The typical psychologic and physiologic characteristics of the illness are discussed, and the multidisciplinary team approach to diagnosis and management is outlined.

    Title Routine Screening Tests for the Adolescent.
    Date May 1987
    Journal Primary Care
    Excerpt

    Routine preventive health examinations for adolescents should be conducted annually, and screening tests are an important part of such periodic evaluations. This article outlines the recommended screening tests for all teenagers, and defines the additional screening tests necessary for high risk youth. Annual health screening interventions serve to encourage the development of health-promoting behaviors and preventive health awareness among adolescents.

    Title Goiter in Pregnant Teenagers.
    Date August 1985
    Journal American Journal of Obstetrics and Gynecology
    Excerpt

    Enlargement of the thyroid gland is common in adolescent girls, but there have been no previous reports of the frequency of goiter in pregnant teenagers. This study was undertaken to determine the prevalence of goiter in 309 consecutive pregnant adolescent patients, ages 11 to 19 years, who presented for prenatal care at the University of California (San Diego) Medical Center Teen OB Clinic. Eighteen patients (6%) were found to have a goiter. Subsequent diagnostic tests revealed that 28% of the patients had autoimmune thyroid disorders (chronic thyroiditis or Graves' disease), and the remainder had nontoxic goiters or subacute thyroiditis. Black patients had significantly more thyroid disease than Mexican-American (p less than 0.01) or white patients (p less than 0.005). The incidence of thyroid problems during pregnancy did not differ significantly from that of 600 nonpregnant teenagers who came to the general Adolescent Medicine Clinic for other health problems. Because abnormalities in thyroid function may have potentially adverse implications for mothers and their infants, we recommend careful evaluation of all pregnant teenagers with goiter to assess maternal thyroid function and to provide treatment if necessary.

    Title Basic Issues in Adolescent Medicine.
    Date February 1985
    Journal Current Problems in Pediatrics
    Title Purification and Properties of Debranching Enzyme from Dogfish Muscle.
    Date April 1977
    Journal Biochemistry
    Excerpt

    Glycogen debranching enzyme (4-alpha-glucanotransferase amylo-1,6-glucosidase, EC 2.4.1.25 + 3.2.1.33) was purified 140-fold from dogfish muscle in a rapid, high-yield procedure that takes advantage of a strong binding of the enzyme to glycogen, and its quantitative adsorption to concanavalin A-Sepharose only when the polysaccharide is present. The final product was hrophoresis in the presence and absence of dodecyl sulfate. A molecular weight of 162,000 +/- 5000 was determined by sedimentation equilibrium analysis in good agreement with the value of 160,000 estimated by gel electrophoresis, but a low-sedimentation constant of 6.5 S suggests that the enzyme is asymmetric. The molecule appears to be made up of a single polypeptide chain with no evidence for multiple repeating sequences: it could not be dissociated into smaller fragments by dodecyl sulfate even after complete carboxymethylation; tryptic cleavage of the native protein yielded only two fragments of molecular weight 20,000 and 140,000 without loss of enzymatic activity. The amino acid composition of the enzyme is reported; no covalently bound phosphate or carbohydrate could be detected. All 32 sulfhydryl groups present were titrated with 5,5'-dithiobis(2-nitrobenzoic acid) under denaturing conditions; eight reacted readily in the native enzyme without loss of catalytic activity, while substitution of eight additional ones lowered the activity by 50%. Inactivation was greatly reduced by glycogen; the polysaccharide also influenced markedly the electrophoretic behavior of the enzyme and large filamentous aggregates were formed when solutions of both were mixed. Purified debranching enzyme releases 3 mumol of glucose min-1 mg-1 at 19 degrees C, pH 6.0, from a glycogen limit dextrin and one-tenth this amount when the native polysaccharide is used as substrate; glycogen is quantitatively degraded in the presence of phosphorylase. None of the usual sugar phosphates or nucleotide effectors of glycolysis affected enzymatic activity. No phosphorylation by either dogfish or rabbit skeletal muscle protein kinase or phosphorylase kinase could be demonstrated, nor any direct interaction with phosphorylase as measured by SH-group reactivity, enzymatic activity, or rate of phosphorylase b to a conversion. Purification of the 160,000 molecular weight M-line protein of skeletal muscle resulted in the quantitative removal of debranching enzyme, indicating that the two proteins are different.

    Title The Facilitator Behavior Index.
    Date January 1975
    Journal Psychological Reports
    Title Empathy: a Quality of an Effective Group Leader.
    Date July 1973
    Journal Psychological Reports
    Title Spectrophotometric Determination of Monophenolase Activity of Tyrosinase Isozymes.
    Date June 1972
    Journal Archives of Biochemistry and Biophysics
    Title Fluctuation in Psychological State During Two Encounter-group Weekends.
    Date November 1971
    Journal Psychological Reports

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