Common Medications and Treatments for Diabetic Nerve Pain

There are many different categories of treatment available to patients with diabetic nerve pain.

 

Treatment Type How it works
Anticonvulsants Anticonvulsants (drugs that are used to treat epilepsy), also decrease diabetic nerve pain by varying degrees. This drug class includes Pregabalin, Gabapentin, and Sodium valproate.
Antidepressants Antidepressants (drugs that are used to treat clinical depression), also decrease diabetic nerve pain by varying degrees. This drug class includes venlafaxine, duloxetine, and amitriptyline.Duloxetine improves quality of life in patients with diabetic nerve pain.
Opioids Decrease pain in patients with diabetic nerve pain.Improve quality of life
Percutaneous electrical nerve stimulation Decreases pain in patients with diabetic nerve pain.Improves sleep
Other pharmacologic agents Capsaicin cream reduces pain in patients with diabetic nerve pain.Isosorbide dinitrate spray reduces pain in patients with diabetic nerve pain.