Common Medications and Treatments to Treat Endometriosis

Drug/Treatment How it works
Hormonal contraception (birth control pills, transdermal patches, vaginal ring) Manages the hormones that stimulate the endometrial implants to grow, helping them to shrink down and decrease or eliminate the pain of mild to moderate endometriosis
Medroxyprogesterone injection Decreases or stops menstruation, thereby shrinking implants and reducing symptoms (Side effect: can cause weight gain and depression)
Gonadotropin-releasing hormone (Gn-RH) agonists and antagonists Medications block production of hormones that stimulate the ovaries, inhibiting menses and decreasing estrogen levels which shrink the endometrial implants; Remission may last years after treatment (Side effects: menopausal symptoms may occur such as hot flashes, mood swings, vaginal dryness, decreased sex drive)
Laparoscopy Finds and removes implants, adhesions, and cysts, or destroys implants with lasers
Hysterectomy Uterus, cervix, and ovaries are removed in severe cases when pregnancy is no longer desired or a possible option
NSAIDS (nonsteroidal pain medication Gives symptomatic relief and decreases swelling (does not treat the implants, but improves daily functioning)
Warm baths/heating pad Decreases discomfort by relaxing pelvic muscles; Decreases cramps

Written by Barbara Hales, M.D.

Local Endometriosis Specialists

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