Multiple sclerosis affects 350,000 people in the U.S. Though the condition can appear at any age, it is most often diagnosed in people between the ages of 20-50 years. MS appears twice as often in Caucasians, and females are affected earlier in life twice as frequently as males. Read more in our patient education guide.
Multiple Sclerosis is a disease whereby the central nervous system components break down and degenerate. Scar tissue can form with resulting plaque in the spinal cord and brain. Myelin, a substance that covers the nerves and supports nerve health, is responsible for impulse conduction. In MS patients, myelin disintegrates through inflammation causing electrical impulses to slow down.
As the condition progresses with nerve damage, various normal functions can be compromised. These include:
Though the cause of multiple sclerosis is unknown, it is highly suspected that a viral infection changes cells of the immune system so that the body, thinking that myelin is an invader, attacks and destroys it. This attack is known as autoimmunity.
There are several types of multiple sclerosis based upon the timing of symptoms.
Doctors Who Treat Multiple Sclerosis
As multiple sclerosis is diagnosed, treated and managed, you may encounter the following team of doctors and specialists. Having a team of doctors or specialists with varied expertise will more accurately help diagnose the possibility of having multiple sclerosis and enable better management of disabling symptoms.
Members of the multiple sclerosis treatment team include:
- Neurologist - Helps diagnose and manage symptoms of multiple sclerosis affecting nerves like shakes, weakness of muscles or limbs and thinking abilities.
- Physiatrist - A doctor who specializes in rehabilitation therapy. This doctor designs a treatment plan to help keep as much function as possible.
- Occupational Therapist - Plans out strategies to help perform tasks that will be needed at work
- Nutritionist - Plans out daily dietary needs, vitamins and meal plans to achieve maximum balanced health
- Physical Therapist - Designs an exercise program to maintain balance, coordination and strength.
- Speech Pathologist - Assesses and formulates exercises to treat communication problems
- Psychologist - Assesses disturbances in mood (depression, anxiety, tension) or mental health associated with multiple sclerosis and provides therapy to improve the problem
- Psychiatrist - Doctor who provides medication or shock therapy to improve mental health issues associated with multiple sclerosis
- Urologist - Doctor who deals with urinary tract problems and supplies advice or medication for any dysfunction in this system due to multiple sclerosis
- Nurse - Provides education for multiple sclerosis and helps coordinate care
- Social worker - Puts patients in touch with support groups and helps with insurance or disability forms as well as any agencies that will be needed for additional services
- Family Physician or Internist - Coordinates care from all the specialists and treats any conditions or disorders that may be occurring simultaneously
How to Prepare for Your Multiple Sclerosis Doctor Visit
Having made your appointment with a healthcare provider, there are certain actions that you need to take in order to maximize the benefit of your multiple sclerosis doctor visit which are listed below in this patient education guide.
- Bring a list of all medications that are currently being taken. Note the dosage of each medication.
- Bring a list of all symptoms experienced, with a time line such as when they started, when they stopped, what made them worse
- Take a list of allergies
- Have a list of all past medical history including surgery, medical problems and the dates of each
For an MRI:
- Wear clothes without any metal
- Remove all jewelry, Glasses, hearing aids, dentures, wallet
- Remove cosmetics/make-up
- Remove any prosthetic devices
Questions to Ask Your Doctor About Multiple Sclerosis
From your initial diagnosis throughout your treatment and care, you will have questions about
multiple sclerosis. Listed in this patient education guide are questions to discuss with your doctor so you can make informed decisions about your condition.
Question About My Diagnosis
- What caused my multiple sclerosis?
- How do you diagnose the condition?
- What type of MS do I have? What stages will I experience?
- Are there other conditions that can be confused with MS? Are there other conditions associated with MS?
- Should I see a specialist?
Questions About My Treatment
- Is there treatment for MS? If so, which do you advise?
- How is the treatment administered? What are the side effects?
- Can the treatment keep me in remission?
- Are there alternative therapies that you recommend?
- Are there clinical trials that I could enroll in?
Questions About My Lifestyle & Family
- Is MS hereditary?
- Are there activities that I should avoid
- Will I still be able to work? Can I drive?
- Is there a special diet that you advise?
- Is there exercise to improve my condition?
Common Tests or Labs to Diagnose Multiple Sclerosis
In recent years, doctors have been able to diagnose multiple sclerosis earlier in patients. It could take years for warning signs and symptoms of the disease to lead to a definitive diagnosis. However, newer techniques have been refined with tests to help rule out any other neurological or muscular condition and come to a conclusive diagnosis.
Currently, there are three benchmark tests in addition to a thorough examination and review of symptom history. They are listed below in this patient education guide:
| Test |
Why Test? |
What Happens? |
What is a Normal/Abnormal Result? |
| Magnetic Resonance Imaging (MRI) |
Visualizes and describes brain defects (plaques) |
A patient lies on a table that slides into a large tunnel-shaped machine. Gadolinium (dye) is injected into the vein to help make the images more clear. |
Abnormal results show plaque or scar tissue along the nerve fibers. |
| Spinal Tap |
Fluid surrounding the spinal cord and brain is analyzed for antibodies, abnormal chemicals or cells |
A patient lies on a table in a curled position and the physician locates the space between the vertebras; a needle with syringe is inserted and fluid is sucked out. |
Abnormal results would reveal antibodies, or white blood cells |
| Electro-Physiological Test |
Assesses nerve impulse transmissions |
A patient lies on a table and electrodes are inserted into the muscles to be tested. Stimulation is applied through the skin over the nerve and the contraction of the muscle records the electric activity. |
Abnormal results would be a slowing of the transmission greater than the expected speed. |
Common Medications and Treatments for Multiple Sclerosis
There are four main objectives to treatment of multiple sclerosis which are listed below in this patient education guide:
- Diminishing the frequency of neurological attacks
- Shortening time to recover from attacks
- Inhibit disease progression
- Relief of complications or side effects of multiple sclerosis
| Drug Category |
How the Medication Works |
| Interferons |
Controls the immune system; protects against viruses and other invaders |
| Disease Modifying Drugs (DMDs) |
Inhibits attack of myelin by the immune system |
| Corticosteroids |
Non-specific effect on the immune system
Decreases inflammation
|
| Monoclonal antibody |
Prevents immune cells from attaching to other cells |
| Chemotherapy |
Destroys abnormal cells |
| Immunomodulating Drug (Oral medication) |
Decreases inflammatory process |
| Muscle Relaxants |
Decreases spasms of muscles |
| Anticonvulsants |
Acts as pain-reliever |
| Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) |
Decreases inflammation around the nerves |
Research into future treatment options of multiple sclerosis centers around myelin manufacture by the brain to block nerve death. Other research focuses on implanting cells into the spinal cord or brain to grow in areas where these cells are missing to promote impulse transmission along the damaged nerves.
Stretching exercises can help to diminish stiffness and increase mobility.
Massage therapy may help with the tightened or spasmodic muscles in multiple sclerosis.