Summary

Dr. James Mastrianni is a neurologist who specializes in treating conditions that affect memory and cognitive function. He earned his medical degree from McGill University Faculty of Medicine and completed his residency training at the University of Pennsylvania Health System. With 37 years of experience in neurology practice, Dr. Mastrianni brings extensive expertise to patient care. He is fluent in both English and Spanish.

Dr. Mastrianni practices at The University of Chicago Medicine and is also affiliated with UChicago Medicine Comer Children's Hospital Hyde Park, both located in Chicago, Illinois. His clinical focus centers on caring for patients with Alzheimer's disease, dementia, and cognitive impairment. He performs diagnostic blood tests and specialized immunology testing to help evaluate neurological conditions. Patients have given him an average rating of 5.0 on Vitals.

Overview based on verified provider data

Quick Facts

  • accepting new patients
  • 5
  • 37 years of experience
  • speaks English, Spanish
  • University Of Pennsylvania Health System
  • 1 written review
  • 1 specialty
  • 13 areas of expertise
  • 2 hospital affiliations
  • 2 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. James A Mastrianni has 2 locations

The University Of Chicago Medicine

5841 S Maryland AveChicago, IL 60637

University Of Chicago Medicine Neurology Clinic

5758 S Maryland Ave Ste 4gChicago, IL 60637
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

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Dr. James A Mastrianni, MDDr. David Calimag, MDDr. Jigisha Paresh Thakkar, MDDr. Valeria Serban, MD
NeurologyNeurologyNeurologyNeurology
Accepts New Patients Accepts New Patients Accepts New Patients Accepts New Patients
4.1 
4.5 
37 Years of Experience 54 Years of Experience 34 Years of Experience
No Virtual Visit Option No Virtual Visit Option No Virtual Visit Option Virtual Visit Available
Speaks English, Spanish Speaks English, Spanish, Tagalog Speaks English
Chicago , ILPark Ridge , ILMaywood , ILNew York , NY
Med School: Mc Gill Univ Fac Of Med Med School: University Of Santo Tomas Faculty Of Medicine And Surgery Med School: Universitatea De Medicina Si Farmacie Iuliu Hatieganu
Current Profile
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Insurance Plans Accepted by Dr. James A Mastrianni

Be sure to verify insurance information directly with your doctor's office, as it may undergo frequent changes.

Medical Specialties

Dr. James A Mastrianni has the following specialty

Specialty Expertise

Dr. James A Mastrianni has the following 13 areas of expertise

  • Alzheimer's Disease
  • Creutzfeldt-Jakob Syndrome (CJD)
  • Dementia Related Behavioral Disorders
  • Electromyography
  • Epilepsy
  • Gerstmann-Straussler-Scheinker Disease
  • Headache
  • Memory Disorders
  • Migraine Disorder
  • Multiple Sclerosis (MS)
  • Nerve Conduction Studies
  • Prion Diseases
  • Stroke

Certifications, License, & Education

37 Years Experience

Dr. James A Mastrianni holds an expired medical license in the state of Illinois.

Medical License

Medical Doctor with an expired medical license in the state of Illinois that expired in 2026.

Education & Training

Residency

Completed their residency at University Of Pennsylvania Health System.

Medical School

Graduated from Mc Gill Univ Fac Of Med in 1989.

NPI Number

Dr. Mastrianni's NPI number is 1821149808.

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Frequently Asked Questions

Is Dr. James Mastrianni accepting new patients?
Dr. James Mastrianni is accepting new patients on Vitals. View Dr. James Mastrianni's profile on Vitals to make an appointment.
Does Dr. James Mastrianni accept my insurance?
You can see the insurance plans that Dr. James Mastrianni accepts on their Vitals profile.
Does Dr. James Mastrianni accept virtual/telehealth appointments?
Dr. James Mastrianni has not indicated that they accept virtual/teleheatlh appointments. Contact their office through their Vitals profile to check for availability.
Which hospitals is Dr. James Mastrianni affiliated with?
Dr. James Mastrianni is affiliated with The University Of Chicago Medicine and Uchicago Medicine Comer Childrens Hospital Hyde Park.
Where is Dr. James Mastrianni's office located?
Dr. James Mastrianni's office is located at 5841 S Maryland Ave, Chicago, IL, 60637.

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