Summary

Dr. Jeffrey Mathews is a gastroenterologist with 38 years of experience treating digestive system disorders. He earned his medical degree from the University of Missouri and completed his residency at Jewish Hospital Washington University in 1991. Dr. Mathews went on to complete a fellowship at St. Louis University in 1993, which provided him with specialized training in gastroenterology. He speaks English with his patients.

Dr. Mathews practices at multiple locations throughout the St. Louis area, including Chesterfield, Saint Louis, and Ballwin. He maintains hospital affiliations with Mercy Hospital Saint Louis and Saint Luke's Hospital. His clinical expertise focuses on treating conditions like colon polyps, diverticular disease, and diverticulosis. Dr. Mathews performs diagnostic procedures including colonoscopies and upper and lower gastrointestinal endoscopies to help diagnose and treat digestive health concerns. Patients rate him 4.8 out of 5 stars on Vitals.

Overview based on verified provider data

Quick Facts

  • accepting new patients
  • 4.8
  • 38 years of experience
  • speaks English
  • St. Louis University
  • 17 written reviews
  • 1 specialty
  • 10 areas of expertise
  • 1 board certification
  • 2 hospital affiliations
  • 5 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. Jeffrey E. Mathews has 5 locations

Gateway Gastroenterology

121 Saint Lukes Center Dr Ste 406Chesterfield, MO 63017
Mon8:00 am - 4:00 pm
Tue8:00 am - 4:00 pm
Wed8:00 am - 4:00 pm
Thu8:00 am - 4:00 pm
Fri8:00 am - 4:00 pm
SatClosed
SunClosed

Gateway Endoscopy Center

12855 N 40 Dr Ste 150Saint Louis, MO 63141
Mon7:00 am - 4:00 pm
Tue7:00 am - 4:00 pm
Wed7:00 am - 4:00 pm
Thu7:00 am - 4:00 pm
Fri7:00 am - 4:00 pm
SatClosed
SunClosed

Gateway Gastroenterology - St. Luke's

121 Saint Lukes Center DrChesterfield, MO 63017
Mon8:00 am - 4:00 pm
Tue8:00 am - 4:00 pm
Wed8:00 am - 4:00 pm
Thu8:00 am - 4:00 pm
Fri8:00 am - 4:00 pm
SatClosed
SunClosed

Saint Louis Multispecialty Surgery Center

884 Woods Mill Rd Ste 100Ballwin, MO 63011
Mon7:30 am - 5:00 pm
Tue7:30 am - 5:00 pm
Wed7:30 am - 5:00 pm
Thu7:30 am - 5:00 pm
Fri7:30 am - 5:00 pm
SatClosed
SunClosed

Saint Lukes Hospital

232 S Woods Mill Rd Ste 330EChesterfield, MO 63017

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Dr. Jeffrey E. Mathews, MDRebecca Humphries, APRNAshley Anderson, APRNShauna Sanderson, APRN
GastroenterologyGastroenterologyGastroenterologyGastroenterology
Accepts New Patients Accepts New Patients Accepts New Patients Accepts New Patients
4.8 
38 Years of Experience
No Virtual Visit Option Virtual Visit Available Virtual Visit Available Virtual Visit Available
Speaks English Speaks English Speaks English Speaks English
Chesterfield , MOSACRAMENTO , CASACRAMENTO , CATallahassee , FL
Med School: University of Missouri Med School: Emory University Med School: East Tennessee State University - Quillen College of Medicine Med School: Creighton University College of Nursing
Current Profile
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Insurance Plans Accepted by Dr. Jeffrey E. Mathews

  • Accepts Medicare
  • Accepts Medicaid

Medical Specialties

Dr. Jeffrey E. Mathews has the following specialty

Specialty Expertise

Dr. Jeffrey E. Mathews has the following 10 areas of expertise

  • Abdominal Pain
  • Acid Reflux Disease (Gastroesophageal Reflux / GERD)
  • Acid Reflux Disease (GERD)
  • Celiac Disease
  • Colonoscopy
  • Constipation
  • Hemorrhoids
  • Hepatitis C
  • Irritable Bowel Syndrome (IBS)
  • Ulcerative Colitis

Certifications, License, & Education

38 Years Experience

Dr. Jeffrey E. Mathews holds an expired medical license in the state of Missouri.

Medical License

Medical Doctor with an expired medical license in the state of Missouri that expired in 2026.

Education & Training

Fellowship

Completed their fellowship at St. Louis University in 1993.

Residency

Completed their residency at Jewish Hospital Washington University in 1991.

Medical School

Graduated from University of Missouri in 1988 and University Of Missouri-Kansas City School Of Medicine in 1988.

NPI Number

Dr. Mathews' NPI number is 1285635656.

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Frequently Asked Questions

Is Dr. Jeffrey Mathews accepting new patients?
Dr. Jeffrey Mathews is accepting new patients on Vitals. View Dr. Jeffrey Mathews's profile on Vitals to make an appointment.
Which hospitals is Dr. Jeffrey Mathews affiliated with?
Dr. Jeffrey Mathews is affiliated with Mercy Hospital Saint Louis and SAINT LUKES HOSPITAL.
How can I make an appointment with Dr. Jeffrey Mathews?
You can find contact information for Dr. Jeffrey Mathews here on Vitals.
Where is Dr. Jeffrey Mathews's office located?
Dr. Jeffrey Mathews's office is located at 121 Saint Lukes Center Dr Ste 406, Chesterfield, MO, 63017.
What languages does Dr. Jeffrey Mathews speak?
Dr. Jeffrey Mathews speaks English.

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