Summary

Dr. John Mattheis is a family medicine physician who earned his medical degree from the University of Iowa. He completed his residency training at McLeod Regional Medical Center, where he developed expertise in comprehensive primary care. With three decades of clinical experience, Dr. Mattheis has built extensive knowledge in managing complex medical conditions. He is fluent in both English and Spanish, allowing him to serve diverse patient populations in the Florence community.

Dr. Mattheis practices at multiple locations throughout Florence, South Carolina, including McLeod Regional Medical Center and McLeod Family Medicine Center. He also provides care at MUSC Health Florence Medical Center and MUSC Health Florence Women's Pavilion. His clinical focus includes treating heart failure and chronic pain conditions. Dr. Mattheis performs routine diagnostic procedures such as complete blood counts and diabetes monitoring tests. Patients have given him an average rating of 4.0, reflecting their confidence in his compassionate and thorough approach to family medicine care.
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Overview based on verified provider data

Quick Facts

  • accepting new patients
  • 4
  • 30 years of experience
  • 21 insurance plans accepted
  • speaks English, Spanish
  • Mcleod Regional Medical Center
  • 1 written review
  • 1 specialty
  • 7 areas of expertise
  • 1 board certification
  • 1 hospital affiliation
  • 4 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. John Ray Mattheis has 4 locations

Mcleod Regional Medical Center

555 E Cheves StFlorence, SC 29506

Mcleod Family Medicine Center

144 N Ravenel StFlorence, SC 29506
Mon8:30 am - 5:00 pm
Tue8:30 am - 5:00 pm
Wed8:30 am - 5:00 pm
Thu8:30 am - 5:00 pm
Fri8:30 am - 5:00 pm
SatClosed
SunClosed

Musc Health Florence Medical Center

805 Pamplico HwyFlorence, SC 29505

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Dr. John Ray Mattheis, MDHelix Virtual CareDr. Shakeilla Smithbey, MDShanekwah Melville, DNP, APRN, FNP-C
Family MedicineFamily MedicineFamily MedicineFamily Medicine
Accepts New Patients Accepts New Patients Accepts New Patients Accepts New Patients
30 Years of Experience 15 Years of Experience 10 Years of Experience
No Virtual Visit Option Virtual Visit Available Virtual Visit Available Virtual Visit Available
Speaks English, Spanish Speaks English Speaks English, Spanish
Florence , SCBoca Raton , FLHouston , TXHouston , TX
Med School: University Of Iowa Med School: Howard University College Of Medicine
Current Profile
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Insurance Plans Accepted by Dr. John Ray Mattheis

  • Aetna
  • Aetna Better Health
  • Aetna Better Health - Medicaid
  • Blue Choice Health Plan
  • Blue Cross Blue Shield
  • Blue Cross Blue Shield of South Carolina
  • CHAMPVA
  • HealthNow
  • Humana
  • Humana - HMO
  • Medicaid - Medicaid
  • Medicaid - Medicaid (Managed)
  • Medicare
  • Medicare - Medicaid (Managed)
  • Medicare - Medicare
  • Molina Healthcare
  • Molina Healthcare - Medicaid (Managed)
  • Optima Health - Medicaid (Managed)
  • Select Health of South Carolina - Medicaid (Managed)
  • UnitedHealthcare
  • Wellcare

Medical Specialties

Dr. John Ray Mattheis has the following specialty

Specialty Expertise

Dr. John Ray Mattheis has the following 7 areas of expertise

  • Check-up
  • Contraception
  • Family Planning
  • Immunization
  • Influenza
  • Preventive Medicine
  • Weight Loss

Certifications, License, & Education

30 Years Experience

Dr. John Ray Mattheis holds an active medical license in the state of South Carolina.

Medical License

Medical Doctor with an active medical license in the state of South Carolina that expires in 2027.

Education & Training

Residency

Completed their residency at Mcleod Regional Medical Center.

Medical School

Graduated from University Of Iowa in 1996.

NPI Number

Dr. Mattheis' NPI number is 1053361329.

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Frequently Asked Questions

Is Dr. John Ray Mattheis accepting new patients?
Dr. John Ray Mattheis is accepting new patients on Vitals. View Dr. John Ray Mattheis's profile on Vitals to make an appointment.
Where is Dr. John Ray Mattheis's office located?
Dr. John Ray Mattheis's office is located at 555 E Cheves St, Florence, SC, 29506.
Does Dr. John Ray Mattheis accept my insurance?
You can see the insurance plans that Dr. John Ray Mattheis accepts on their Vitals profile.
How can I make an appointment with Dr. John Ray Mattheis?
You can find contact information for Dr. John Ray Mattheis here on Vitals.
Which hospitals is Dr. John Ray Mattheis affiliated with?
Dr. John Ray Mattheis is affiliated with Mcleod Regional Medical Center.

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