Summary

Dr. Mark Liker is a board-certified neurosurgeon and the founder and senior partner of California Neurosurgical Institute. He performs 400–500 successful spine and brain surgeries each year in Valencia and Encino. With over 20 years of expertise in minimally invasive, endoscopic, and open techniques—including artificial disc replacement, microdiscectomies, peripheral nerve surgery, functional neurosurgery, radiosurgery, and minimally invasive spinal fusions—he combines world-class surgical precision with a patient-first philosophy. Drawing on his unique background as a mechanical and aerospace engineer at Princeton University and advanced SPECT-CT imaging, Dr. Liker delivers personalized treatment plans that target the root cause of pain and accelerate recovery.Dr. Liker provides expert care for conditions including... Brain TumorBack PainSciatica and Pinched NerveSlipped, Degenerated, and Herniated DiscsTraumatic Brain InjuryConcussionSpinal Cord CompressionPeripheral Nerve PainSpinal StenosisTrigeminal NeuralgiaHemifacial SpasmRenowned for his problem-solving approach and academic leadership, Dr. Liker has been named a Castle Connolly Top Doctor for 15 consecutive years, recognized as a Southern California Super Doctor from 2013–2022, and ranked among the top 1% of U.S. neurosurgeons by U.S. News & World Report. As an assistant professor at the Keck School of Medicine of USC, he has authored over 40 peer-reviewed manuscripts, edited three journal special editions, and delivered more than 40 national and international presentations—continuously advancing neurosurgical care and deep brain stimulation techniques to help patients get back to life with durable, long-term relief.We would love to make a difference for you. Chat Now with us Today!
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Quick Facts

  • accepting new patients
  • 4.1
  • 31 years of experience
  • speaks English
  • Lac Usc Medical Center
  • 33 written reviews
  • 2 specialties
  • 21 areas of expertise
  • 2 board certifications
  • 5 hospital affiliations
  • 9 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. Mark Andrew Liker has 9 locations

California Neurosurgical Institute Valencia

23929 McBean Pkwy Ste 215Valencia, CA 91355
Mon9:00 am - 5:00 pm
Tue9:00 am - 5:00 pm
Wed9:00 am - 5:00 pm
Thu9:00 am - 5:00 pm
Fri9:00 am - 5:00 pm
SatClosed
SunClosed

Usc Neurosurgery Clinic

1520 San Pablo St Ste 3800Los Angeles, CA 90033
Mon8:30 am - 4:30 pm
Tue8:30 am - 4:30 pm
Wed8:30 am - 4:30 pm
Thu8:30 am - 4:30 pm
Fri8:30 am - 4:30 pm
SatClosed
SunClosed

California Neurosurgical Institute Encino

16260 VENTURA BLVD STE 700ENCINO, CA 91436
Mon9:00 am - 5:00 pm
Tue9:00 am - 5:00 pm
Wed9:00 am - 5:00 pm
Thu9:00 am - 5:00 pm
Fri9:00 am - 5:00 pm
SatClosed
SunClosed

Dignity Health Northridge Hospital Medical Center

18300 Roscoe BlvdNorthridge, CA 91325

Bakersfield Heart Hospital

3001 Sillect AveBakersfield, CA 93308

Ucla Santa Clarita Valley Cancer Center

23929 McBean Pkwy Ste 215Valencia, CA 91355
Mon9:00 am - 5:00 pm
Tue9:00 am - 5:00 pm
Wed9:00 am - 5:00 pm
Thu9:00 am - 5:00 pm
Fri9:00 am - 5:00 pm
SatClosed
SunClosed

Disc Surgery Center At Newport Beach

3501 Jamboree Rd Ste 1200Newport Beach, CA 92660
Mon8:30 am - 5:00 pm
Tue8:30 am - 5:00 pm
Wed8:30 am - 5:00 pm
Thu8:30 am - 5:00 pm
Fri8:30 am - 5:00 pm
SatClosed
SunClosed

Keck Hospital Of Usc

1500 San Pablo StLos Angeles, CA 90033

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Dr. Mark Andrew Liker, MDDr. Kevin Gerard Waldron, MDDr. Lawrence San LiuDr. Julian Antony Mattiello, MD
Neurological SurgeryNeurological SurgeryNeurological SurgeryNeurological Surgery
Accepts New Patients Accepts New Patients
4.1 
4.7 
31 Years of Experience 27 Years of Experience 35 Years of Experience 26 Years of Experience
No Virtual Visit Option Virtual Visit Available No Virtual Visit Option No Virtual Visit Option
Speaks English Speaks English
Valencia , CALaguna Hills , CALos Angeles , CALos Angeles , CA
Med School: Suny Downstate Medical Center College Of Medicine Med School: Rutgers Robert Wood Johnson Medical School Med School: New York University School Of Medicine Med School: Lewis Katz School Of Medicine At Temple University
Current Profile
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Insurance Plans Accepted by Dr. Mark Andrew Liker

  • Accepts Medicaid

Medical Specialties

Dr. Mark Andrew Liker has the following 2 specialties

Specialty Expertise

Dr. Mark Andrew Liker has the following 21 areas of expertise

  • Aneurysm
  • Back Injuries
  • Back Pain
  • Brain Surgery
  • Brain Tumor
  • Craniotomy
  • Dystonia
  • Essential Tremor
  • Gamma Knife Surgery (Stereotactic Radiosurgery)
  • Glioblastoma
  • Head and Neck Disorder
  • Infection
  • Laminectomy
  • Movement Disorders
  • Neurology
  • Neurosurgery
  • Neurosurgical Procedures
  • Parkinson Disease
  • Spinal Fractures
  • Spinal Stenosis
  • Stroke

Certifications, License, & Education

31 Years Experience

Education & Training

Residency

Completed their residency at Lac Usc Medical Center.

Medical School

Graduated from Suny Downstate Medical Center College Of Medicine in 1995.

NPI Number

Dr. Liker's NPI number is 1407806292.

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Frequently Asked Questions

Does Dr. Mark Liker accept my insurance?
You can see the insurance plans that Dr. Mark Liker accepts on their Vitals profile.
What languages does Dr. Mark Liker speak?
Dr. Mark Liker speaks English.
Is Dr. Mark Liker accepting new patients?
Dr. Mark Liker is accepting new patients on Vitals. View Dr. Mark Liker's profile on Vitals to make an appointment.
How can I make an appointment with Dr. Mark Liker?
You can find contact information for Dr. Mark Liker here on Vitals.
Which hospitals is Dr. Mark Liker affiliated with?
Dr. Mark Liker is affiliated with Bakersfield Heart Hospital, Dignity Health Northridge Hospital Medical Center, Keck Hospital Of Usc, Providence Cedars Sinai Tarzana Medical Center, and Henry Mayo Newhall Memorial Hospital.

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