Summary

Dr. Santo Difino is an internal medicine physician who specializes in hematology and oncology, bringing over five decades of medical expertise to his practice. He earned his medical degree from Rutgers New Jersey Medical School and completed his residency at SUNY Health Science Center. With 52 years of experience treating patients, Dr. Difino has developed extensive knowledge in diagnosing and managing blood disorders and cancer care. He is fluent in both English and Spanish, allowing him to serve a diverse patient population.

Dr. Difino practices at multiple locations throughout Syracuse, including Upstate Community Hospital, Saint Joseph's Hospital Health Center, and Hematology Oncology Associates of Central New York in East Syracuse. His affiliation with Crouse Hospital further expands his ability to provide comprehensive care to patients in the region. Patients consistently rate their experience with him highly, giving him an average rating of 4.4 out of 5 stars. His dual expertise in hematology and oncology enables him to address complex blood-related conditions and provide cancer treatment with the depth of knowledge that comes from decades of specialized practice.
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Overview based on verified provider data

Quick Facts

  • accepting new patients
  • 4.4
  • 52 years of experience
  • 14 insurance plans accepted
  • speaks English, Spanish
  • Suny Health Science Center
  • 2 written reviews
  • 3 specialties
  • 15 areas of expertise
  • 3 board certifications
  • 1 hospital affiliation
  • 4 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. Santo Michael Difino has 4 locations

Upstate Community Hospital

4900 Broad RdSyracuse, NY 13215
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Hematology Oncology Associates Of Central New York

5008 Brittonfield Pkwy Ste 700East Syracuse, NY 13057
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Hematology Oncology Associates Of Central New York

5008 Brittonfield PkwyEast Syracuse, NY 13057
Mon8:00 am - 6:00 pm
Tue8:00 am - 6:00 pm
Wed8:00 am - 6:00 pm
Thu8:00 am - 6:00 pm
Fri8:00 am - 6:00 pm
SatClosed
SunClosed

Saint Josephs Hospital Health Center

301 Prospect AveSyracuse, NY 13203

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Dr. Santo Michael Difino, MDDr. Eric Yoon, MDDr. Arthur Yunov, MDEric Harker
Internal MedicineInternal MedicineInternal MedicineInternal Medicine
Accepts New Patients Accepts New Patients Accepts New Patients Accepts New Patients
4.4 
52 Years of Experience 34 Years of Experience 25 Years of Experience
No Virtual Visit Option Virtual Visit Available Virtual Visit Available Virtual Visit Available
Speaks English, Spanish Speaks English Speaks English Speaks English
Syracuse , NYNew York , NYBrooklyn , NYLyons , CO
Med School: Rutgers New Jersey Medical School Med School: State University of New York Med School: ANDIZHAN STATE MEDICAL INSTITUTE Med School: Duke University School Of Medicine
Current Profile
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Insurance Plans Accepted by Dr. Santo Michael Difino

  • Aetna
  • Blue Cross Blue Shield
  • Empire Plan
  • Fidelis Care (NY)
  • Humana - Medicare (Advantage HMO)
  • Medicaid
  • Medicaid - Medicaid
  • Medicare
  • Medicare - Medicare
  • MVP Health Care
  • UnitedHealthcare
  • UnitedHealthcare - HMO
  • UnitedHealthcare - Medicare
  • UnitedHealthcare - Medicare (Advantage HMO)

Medical Specialties

Dr. Santo Michael Difino has the following 3 specialties

Specialty Expertise

Dr. Santo Michael Difino has the following 15 areas of expertise

  • Acute Myeloid Leukemia
  • Adult T-Cell Leukemia-Lymphoma
  • Bone Marrow Transplant
  • Cancer
  • Chemotherapy
  • Chronic B-Cell Lymphocytic Leukemia
  • Chronic Myelomonocytic Leukemia
  • Deep Vein Thrombosis
  • Hematology
  • Hepatitis C
  • Leukemia
  • Lymphoma
  • Myelofibrosis
  • Myeloma
  • Oncology

Certifications, License, & Education

52 Years Experience

Education & Training

Residency

Completed their residency at Suny Health Science Center.

Medical School

Graduated from Rutgers New Jersey Medical School in 1974.

NPI Number

Dr. Difino's NPI number is 1225017692.

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Frequently Asked Questions

Is Dr. Santo Difino accepting new patients?
Dr. Santo Difino is accepting new patients on Vitals. View Dr. Santo Difino's profile on Vitals to make an appointment.
Where is Dr. Santo Difino's office located?
Dr. Santo Difino's office is located at 4900 Broad Rd, Syracuse, NY, 13215.
How can I make an appointment with Dr. Santo Difino?
You can find contact information for Dr. Santo Difino here on Vitals.
What languages does Dr. Santo Difino speak?
Dr. Santo Difino speaks English and Spanish.
Which hospitals is Dr. Santo Difino affiliated with?
Dr. Santo Difino is affiliated with Crouse Hospital.

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