Summary

Dr. Santo Difino is an internal medicine physician who specializes in hematology and oncology, bringing over five decades of medical expertise to his practice. He earned his medical degree from Rutgers New Jersey Medical School and completed his residency at SUNY Health Science Center. With 52 years of experience treating patients, Dr. Difino has developed deep knowledge in blood disorders and cancer care. He is fluent in both English and Spanish, enabling him to serve a diverse patient population.

Dr. Difino is affiliated with Crouse Hospital and practices at multiple locations throughout Syracuse. His clinical focus includes diagnosing and treating conditions such as colon polyps and osteoarthritis. He performs important procedures like colonoscopies and lower GI endoscopies to help detect and monitor digestive health issues. Patients have rated Dr. Difino 4.4 out of 5 stars, reflecting their confidence in his care and expertise.

AI-generated from data on this provider profile.

Quick Facts

  • accepting new patients
  • 4.4
  • 52 years of experience
  • 14 insurance plans accepted
  • speaks English, Spanish
  • Suny Health Science Center
  • 2 written reviews
  • 3 specialties
  • 15 areas of expertise
  • 3 board certifications
  • 1 hospital affiliation
  • 4 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. Santo Michael Difino has 4 locations

Upstate Community Hospital

4900 Broad RdSyracuse, NY 13215
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Hematology Oncology Associates Of Central New York

5008 Brittonfield Pkwy Ste 700East Syracuse, NY 13057
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Hematology Oncology Associates Of Central New York

5008 Brittonfield PkwyEast Syracuse, NY 13057
Mon8:00 am - 6:00 pm
Tue8:00 am - 6:00 pm
Wed8:00 am - 6:00 pm
Thu8:00 am - 6:00 pm
Fri8:00 am - 6:00 pm
SatClosed
SunClosed

Saint Josephs Hospital Health Center

301 Prospect AveSyracuse, NY 13203

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Dr. Santo Michael Difino, MDEric HarkerNatalie Howard, MSN, DNPDr. Eric Yoon, MD
Internal MedicineInternal MedicineInternal MedicineInternal Medicine
Accepts New Patients Accepts New Patients Accepts New Patients Accepts New Patients
4.4 
3.9 
52 Years of Experience 25 Years of Experience 6 Years of Experience
No Virtual Visit Option Virtual Visit Available Virtual Visit Available Virtual Visit Available
Speaks English, Spanish Speaks English Speaks English Speaks English
Syracuse , NYLyons , CONew York City , NYNew York , NY
Med School: Rutgers New Jersey Medical School Med School: Duke University School Of Medicine Med School: State University of New York
Current Profile
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Insurance Plans Accepted by Dr. Santo Michael Difino

  • Aetna
  • Blue Cross Blue Shield
  • Empire Plan
  • Fidelis Care (NY)
  • Humana - Medicare (Advantage HMO)
  • Medicaid
  • Medicaid - Medicaid
  • Medicare
  • Medicare - Medicare
  • MVP Health Care
  • UnitedHealthcare
  • UnitedHealthcare - HMO
  • UnitedHealthcare - Medicare
  • UnitedHealthcare - Medicare (Advantage HMO)

Medical Specialties

Dr. Santo Michael Difino has the following 3 specialties

Specialty Expertise

Dr. Santo Michael Difino has the following 15 areas of expertise

  • Acute Myeloid Leukemia
  • Adult T-Cell Leukemia-Lymphoma
  • Bone Marrow Transplant
  • Cancer
  • Chemotherapy
  • Chronic B-Cell Lymphocytic Leukemia
  • Chronic Myelomonocytic Leukemia
  • Deep Vein Thrombosis
  • Hematology
  • Hepatitis C
  • Leukemia
  • Lymphoma
  • Myelofibrosis
  • Myeloma
  • Oncology

Certifications, License, & Education

52 Years Experience

EDUCATION & TRAINING

Residency

Suny Health Science Center

Medical School

Rutgers New Jersey Medical SchoolGraduated in 1974

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Frequently Asked Questions

Where is Dr. Santo Difino's office located?
Dr. Santo Difino's office is located at 4900 Broad Rd, Syracuse, NY, 13215.
Which hospitals is Dr. Santo Difino affiliated with?
Dr. Santo Difino is affiliated with Crouse Hospital.
What languages does Dr. Santo Difino speak?
Dr. Santo Difino speaks English and Spanish.
Does Dr. Santo Difino accept my insurance?
You can see the insurance plans that Dr. Santo Difino accepts on their Vitals profile.
Does Dr. Santo Difino accept virtual/telehealth appointments?
Dr. Santo Difino has not indicated that they accept virtual/teleheatlh appointments. Contact their office through their Vitals profile to check for availability.

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