Summary

Dr. William Mazzella is a board-certified physician specializing in internal medicine, critical care medicine, and hospital medicine. He earned his medical degree from the University of North Carolina at Chapel Hill School of Medicine and brings 28 years of clinical experience to his practice. Dr. Mazzella's expertise spans multiple areas of internal medicine, with particular focus on critically ill patients requiring specialized hospital-based care.

Dr. Mazzella practices at Prisma Health Hillcrest Hospital in Simpsonville, South Carolina, and maintains affiliations with several regional medical centers including Mission Hospital, Central Carolina Hospital, and Prisma Health Greenville Memorial Hospital. He specializes in treating patients with chronic obstructive pulmonary disease and other chronic lung conditions. His clinical work includes ordering comprehensive blood work and chemistry panels to monitor patient health. Patients rate Dr. Mazzella 4.0 out of 5 stars for his care.

Overview based on verified provider data

Quick Facts

  • 4
  • 28 years of experience
  • University Of North Carolina At Chapel Hill School Of Medicine
  • 1 written review
  • 3 specialties
  • 6 areas of expertise
  • 3 board certifications
  • 11 hospital affiliations
  • 4 office locations
  • Male

Patients’ Perspective

  • Had a good bedside manner
  • Spent time with me
  • Provided follow-up after the visit

Office Locations

Dr. William Joseph Mazzella has 4 locations

Prisma Health Hillcrest Hospital

729 Se Main StSimpsonville, SC 29681

Central Carolina Hospital

1135 Carthage StSanford, NC 27330

Inova Mount Vernon Hospital

2501 Parkers LnAlexandria, VA 22306

Prisma Health Greenville Memorial Hospital

701 Grove RdGreenville, SC 29605

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Dr. William Joseph Mazzella, MDDr. Balasubramanyam Krishniah, MDDr. Brian T Gorman, DODr. Norris I Boone, MD
Internal MedicineInternal MedicineInternal MedicineInternal Medicine
Accepts New Patients Accepts New Patients
28 Years of Experience 33 Years of Experience
No Virtual Visit Option No Virtual Visit Option Virtual Visit Available No Virtual Visit Option
Speaks English, Kannada, Hindi, Telugu, Tamil Speaks English
Simpsonville , SCMauldin , SCMyrtle Beach , SCTaylors , SC
Med School: University Of North Carolina At Chapel Hill School Of Medicine Med School: Mysore Medical College And Research Institute Med School: Campbell University School of Osteopathic Medicine
Current Profile
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Insurance Plans Accepted by Dr. William Joseph Mazzella

Be sure to verify insurance information directly with your doctor's office, as it may undergo frequent changes.

Medical Specialties

Dr. William Joseph Mazzella has the following 3 specialties

Specialty Expertise

Dr. William Joseph Mazzella has the following 6 areas of expertise

  • Chest Pain
  • Critical Care Medicine
  • Gastrointestinal Bleeding
  • Hospital Medicine
  • Meningitis
  • Pneumonia

Certifications, License, & Education

28 Years Experience

Dr. William Joseph Mazzella holds active and expired medical licenses in the states of South Carolina and Virginia.

Medical License

Medical Doctor with an active medical license in the state of South Carolina that expires in 2027 and an expired medical license in the state of Virginia that expired in 2026.

Education & Training

Medical School

Graduated from University Of North Carolina At Chapel Hill School Of Medicine in 1998.

NPI Number

Dr. Mazzella's NPI number is 1528158227.

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Frequently Asked Questions

How can I make an appointment with Dr. William Mazzella?
You can find contact information for Dr. William Mazzella here on Vitals.
Where is Dr. William Mazzella's office located?
Dr. William Mazzella's office is located at 729 Se Main St, Simpsonville, SC, 29681.
Which hospitals is Dr. William Mazzella affiliated with?
Dr. William Mazzella is affiliated with Saint Francis Medical Center, Mission Hospital, Central Carolina Hospital, Carolina Pines Regional Medical Center, Prisma Health Hillcrest Hospital, Inova Mount Vernon Hospital, Prisma Health Greenville Memorial Hospital, Specialty Extended Care Hospital, Mission Hospital Saint Joseph Campus, Inova Alexandria Hospital, and Inova Specialty Hospital Mount Vernon.
Does Dr. William Mazzella accept virtual/telehealth appointments?
Dr. William Mazzella has not indicated that they accept virtual/teleheatlh appointments. Contact their office through their Vitals profile to check for availability.
Does Dr. William Mazzella accept my insurance?
You can see the insurance plans that Dr. William Mazzella accepts on their Vitals profile.

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