Summary

University Neurosurgery treats a broad spectrum of adult spinal and brain disorders. Our focus is on minimally invasive, state of the art spine and brain surgery. In addition to standard neurosurgical and microsurgical techniques, we employ minimally invasive techniques such as Metrix percutaneous discectomy, Sextant percutaneous pedicle screw fixation, image-guided brain and spine surgery, endoscopic pituitary surgery, X-stop interspinous process decompression, and kyphoplasty. We utilize Cyberknife radiosurgery to treat certain brain and spinal tumors as well as selected cases of trigeminal neuralgia.
Dr. Killleffer has practiced neurosurgery in Knoxville for eleven years. Prior to moving to Knoxville, he was a full-time member of the academic faculty of the Department of Neurosurgery at West Virginia University, where he served as Instructor of Neurosurgery. Dr. Killeffer is currently the Chief of the Division of Neurosurgeon in the Department of Surgery at the University of Tennessee Graduate School of Medicine where he teaches the surgical residents and medical students. He practices at both University of Tennessee Medical Center and Fort Sanders Regiona Medical Center and is an MD Anderson Cancer Center Credentialed Physician. He has been a compensated consultant for Medtronic Spine and is engaged in active collaborative research invoving head injury and intracranial pressure with scientists at Oak Ridge National Laboratory.
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Quick Facts

  • accepting new patients
  • 4.7
  • 35 years of experience
  • speaks English, Spanish
  • West Virginia University Hospital
  • 45 written reviews
  • 1 specialty
  • 8 areas of expertise
  • 1 board certification
  • 2 hospital affiliations
  • 3 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. James A Killeffer has 3 locations

Neurosurgical Associates Pc

2100 Clinch Ave Ste 110Knoxville, TN 37916
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

University Of Tennessee Medical Center

1924 Alcoa HwyKnoxville, TN 37920

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Dr. James A Killeffer, MDDr. Jonathan David York, MDDr. David Hans Hauge, MDDr. William Stuart Reid, MD
Neurological SurgeryNeurological SurgeryNeurological SurgeryNeurological Surgery
Accepts New Patients Accepts New Patients
4.7 
4.2 
3.6 
35 Years of Experience 16 Years of Experience 42 Years of Experience 55 Years of Experience
No Virtual Visit Option No Virtual Visit Option No Virtual Visit Option No Virtual Visit Option
Speaks English, Spanish Speaks English, Spanish Speaks Spanish, English Speaks Spanish, English
Knoxville , TNKnoxville , TNKnoxville , TNKnoxville , TN
Med School: University Of Tennessee Health Science Center College Of Medicine Med School: Wake Forest School Of Medicine Med School: West Virginia University School Of Medicine Med School: University Of Arizona College Of Medicine
Current Profile
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Insurance Plans Accepted by Dr. James A Killeffer

  • Accepts Medicare
  • Accepts Medicaid

Medical Specialties

Dr. James A Killeffer has the following specialty

Specialty Expertise

Dr. James A Killeffer has the following 8 areas of expertise

  • Aneurysm
  • Brain Surgery
  • Brain Tumor
  • Craniotomy
  • Glioblastoma
  • Laminectomy
  • Neurosurgical Procedures
  • Stroke

Certifications, License, & Education

35 Years Experience

MEDICAL LICENSE

Medical Doctor, Tennessee, 2026, Expired

EDUCATION & TRAINING

Residency

West Virginia University Hospital

Medical School

University Of Tennessee Health Science Center College Of MedicineGraduated in 1991

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Frequently Asked Questions

Is Dr. James Killeffer accepting new patients?
Dr. James Killeffer is accepting new patients on Vitals. View Dr. James Killeffer's profile on Vitals to make an appointment.
What languages does Dr. James Killeffer speak?
Dr. James Killeffer speaks English and Spanish.
Does Dr. James Killeffer accept virtual/telehealth appointments?
Dr. James Killeffer has not indicated that they accept virtual/teleheatlh appointments. Contact their office through their Vitals profile to check for availability.
Which hospitals is Dr. James Killeffer affiliated with?
Dr. James Killeffer is affiliated with University Of Tennessee Medical Center and Fort Sanders Regional Medical Center.
How can I make an appointment with Dr. James Killeffer?
You can find contact information for Dr. James Killeffer here on Vitals.

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