Summary

Dr. William Karnes is a board-certified gastroenterologist and internal medicine physician with 44 years of medical experience. He earned his medical degree from the University of Minnesota Medical School and has dedicated his career to diagnosing and treating digestive system disorders. Dr. Karnes speaks English and brings extensive expertise to his practice.

Dr. Karnes maintains hospital affiliations with Tibor Rubin VA Medical Center and practices across multiple locations in California, including Irvine, Orange, Costa Mesa, and Modesto. He specializes in treating conditions such as colon polyps, GERD, and acid reflux. His procedural expertise includes performing colonoscopies, upper GI endoscopies, and lower GI endoscopies to diagnose and treat digestive health issues. Patients have given Dr. Karnes an average rating of 4.4 out of 5 stars.

Overview based on verified provider data

Quick Facts

  • accepting new patients
  • 4.4
  • 44 years of experience
  • speaks English
  • University Of Minnesota Medical School
  • 8 written reviews
  • 2 specialties
  • 1 area of expertise
  • 5 hospital affiliations
  • 10 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. William Ernest Karnes has 10 locations

Uci Health H H Chao Comprehensive Digestive Disease Center

101 The City Dr S Bldg 22COrange, CA 92868
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Dr. William Ernest Karnes

1 Medical Plaza Drive Gottschalk Medical PlazaIrvine, CA 92697

Dr. William Ernest Karnes

101 The City Dr S Bldg 22COrange, CA 92868
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Uci Medical Center

101 The City Dr SOrange, CA 92868

College Hospital Costa Mesa

301 Victoria StCosta Mesa, CA 92627

Dr. William Ernest Karnes

1 Medical Plaza DriveIrvine, CA 92697

Dr. William Ernest Karnes

1640 Newport Blvd Ste 350Costa Mesa, CA 92627
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Dr. William Ernest Karnes

1640 Newport Blvd Ste 100Costa Mesa, CA 92627

Uci Health Digestive Disease Center

1640 Newport Blvd Ste 350Costa Mesa, CA 92627
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

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Dr. William Ernest Karnes, MDJi Soo Choi, APRNRebecca Humphries, APRNAshley Anderson, APRN
GastroenterologyGastroenterologyGastroenterologyGastroenterology
Accepts New Patients Accepts New Patients Accepts New Patients Accepts New Patients
4.4 
44 Years of Experience
No Virtual Visit Option Virtual Visit Available Virtual Visit Available Virtual Visit Available
Speaks English Speaks English Speaks English Speaks English
Orange , CASACRAMENTO , CASACRAMENTO , CASACRAMENTO , CA
Med School: University Of Minnesota Medical School Med School: New York University Med School: Emory University Med School: East Tennessee State University - Quillen College of Medicine
Current Profile
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Insurance Plans Accepted by Dr. William Ernest Karnes

  • Accepts Medicare
  • Accepts Medicaid

Medical Specialties

Dr. William Ernest Karnes has the following 2 specialties

Specialty Expertise

Dr. William Ernest Karnes has the following area of expertise

  • Internal Medicine

Certifications, License, & Education

44 Years Experience

Dr. William Ernest Karnes holds an expired medical license in the state of California.

Medical License

Medical Doctor with an expired medical license in the state of California that expired in 2026.

Education & Training

Medical School

Graduated from University Of Minnesota Medical School in 1982.

NPI Number

Dr. Karnes' NPI number is 1881652998.

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Frequently Asked Questions

Where is Dr. William Karnes's office located?
Dr. William Karnes's office is located at 101 The City Dr S Bldg 22C, Orange, CA, 92868.
Which hospitals is Dr. William Karnes affiliated with?
Dr. William Karnes is affiliated with Uci Medical Center, Doctors Medical Center Of Modesto, Hoag Hospital Newport Beach, College Hospital Costa Mesa, and Uci Health Irvine.
Does Dr. William Karnes accept my insurance?
You can see the insurance plans that Dr. William Karnes accepts on their Vitals profile.
Does Dr. William Karnes accept virtual/telehealth appointments?
Dr. William Karnes has not indicated that they accept virtual/teleheatlh appointments. Contact their office through their Vitals profile to check for availability.
What languages does Dr. William Karnes speak?
Dr. William Karnes speaks English.

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