Summary

Dr. William Karnes is a gastroenterologist and internal medicine physician who earned his medical degree from the University of Minnesota Medical School. With 44 years of experience in practice, he has developed extensive expertise in digestive health and comprehensive internal medicine care. Dr. Karnes communicates with patients in English.

Dr. Karnes practices at multiple locations throughout California, including Orange, Irvine, Costa Mesa, and Modesto, with affiliations at UCI Medical Center, Hoag Hospital Newport Beach, and other respected healthcare facilities. He specializes in treating conditions such as colon polyps, GERD, and abdominal pain. His procedural expertise includes performing colonoscopies, upper and lower GI endoscopies to diagnose and treat digestive disorders. Patients rate Dr. Karnes 4.4 out of 5 stars on average.

Overview based on verified provider data

Quick Facts

  • accepting new patients
  • 4.4
  • 44 years of experience
  • speaks English
  • University Of Minnesota Medical School
  • 8 written reviews
  • 2 specialties
  • 1 area of expertise
  • 5 hospital affiliations
  • 10 office locations
  • Male

Patients’ Perspective

  • Gave an accurate diagnosis
  • Had a good bedside manner
  • Spent time with me

Office Locations

Dr. William Ernest Karnes has 10 locations

Uci Health H H Chao Comprehensive Digestive Disease Center

101 The City Dr S Bldg 22COrange, CA 92868
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Dr. William Ernest Karnes

1 Medical Plaza Drive Gottschalk Medical PlazaIrvine, CA 92697

Dr. William Ernest Karnes

101 The City Dr S Bldg 22COrange, CA 92868
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Uci Medical Center

101 The City Dr SOrange, CA 92868

College Hospital Costa Mesa

301 Victoria StCosta Mesa, CA 92627

Dr. William Ernest Karnes

1 Medical Plaza DriveIrvine, CA 92697

Dr. William Ernest Karnes

1640 Newport Blvd Ste 350Costa Mesa, CA 92627
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

Dr. William Ernest Karnes

1640 Newport Blvd Ste 100Costa Mesa, CA 92627

Uci Health Digestive Disease Center

1640 Newport Blvd Ste 350Costa Mesa, CA 92627
Mon8:00 am - 5:00 pm
Tue8:00 am - 5:00 pm
Wed8:00 am - 5:00 pm
Thu8:00 am - 5:00 pm
Fri8:00 am - 5:00 pm
SatClosed
SunClosed

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Dr. William Ernest Karnes JR., MDTheresa Obonyano, APRNRachel Oliver, APRNJan Seiler, APRN
GastroenterologyGastroenterologyGastroenterologyGastroenterology
Accepts New Patients Accepts New Patients Accepts New Patients Accepts New Patients
4.4 
44 Years of Experience
No Virtual Visit Option Virtual Visit Available Virtual Visit Available Virtual Visit Available
Speaks English Speaks English Speaks English Speaks English
Orange , CASacramento , CASacramento , CAMontgomery , AL
Med School: University Of Minnesota Medical School Med School: The University of Texas Health Science Center at Houston Med School: University of South Alabama Med School: Georgia State University
Current Profile
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Insurance Plans Accepted by Dr. William Ernest Karnes

  • Accepts Medicare
  • Accepts Medicaid

Medical Specialties

Dr. William Ernest Karnes has the following 2 specialties

Specialty Expertise

Dr. William Ernest Karnes has the following area of expertise

  • Internal Medicine

Certifications, License, & Education

44 Years Experience

Dr. William Ernest Karnes holds an expired medical license in the state of California.

Medical License

Medical Doctor with an expired medical license in the state of California that expired in 2026.

Education & Training

Medical School

Graduated from University Of Minnesota Medical School in 1982.

NPI Number

Dr. Karnes' NPI number is 1881652998.

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Frequently Asked Questions

Is Dr. William Karnes accepting new patients?
Dr. William Karnes is accepting new patients on Vitals. View Dr. William Karnes's profile on Vitals to make an appointment.
How can I make an appointment with Dr. William Karnes?
You can find contact information for Dr. William Karnes here on Vitals.
Does Dr. William Karnes accept my insurance?
You can see the insurance plans that Dr. William Karnes accepts on their Vitals profile.
Does Dr. William Karnes accept virtual/telehealth appointments?
Dr. William Karnes has not indicated that they accept virtual/teleheatlh appointments. Contact their office through their Vitals profile to check for availability.
What languages does Dr. William Karnes speak?
Dr. William Karnes speaks English.

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